American Journal of Medical Case Reports. 2021, 9(11), 544-547
DOI: 10.12691/AJMCR-9-11-7
Calciphylaxis in a Young Adult with Acute Kidney Injury and Recently Diagnosed End-stage Liver Disease
Rachel Russell1, Walid Omer2, Nagat Mudabal2 and Karolyn A. Wanat3,
1Medical College of Wisconsin, Milwaukee, United States
2Department of Nephrology, Medical College of Wisconsin, Milwaukee, United States
3Department of Dermatopathology, Medical College of Wisconsin, Milwaukee, United States
Pub. Date: July 18, 2021
Cite this paper
Rachel Russell, Walid Omer, Nagat Mudabal and Karolyn A. Wanat. Calciphylaxis in a Young Adult with Acute Kidney Injury and Recently Diagnosed End-stage Liver Disease.
American Journal of Medical Case Reports. 2021; 9(11):544-547. doi: 10.12691/AJMCR-9-11-7
Abstract
Calciphylaxis is a rare condition in which calcification of medium blood vessels in the skin results in the purpura and painful, necrotic skin ulcers. Although most commonly seen in adults with end-stage kidney disease and long-term dialysis use, reports of nonuremic calciphylaxis exist. We present the case of a 29-year old woman with recently diagnosed end-stage liver disease who presented with an acute kidney injury and painful lower extremity purpura and ulcers with biopsy-confirmed calciphylaxis. The patient had been receiving dialysis for less than one month. Treatment with sodium thiosulfate was provided but was unsuccessful. The patient ultimately pursued palliative care.
Keywords
calciphylaxis, end-stage liver disease, acute kidney injury
Copyright
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