by Mohammad Asif
Review Article
Acute Heart failure (AHF), clinical signs of low cardiac output, therapy with positive inotropic drug for cardiac care is mandatory. Three classes of inotropic drugs are currently available, like β-adrenergic agonists (especially dobutamine), phosphodiesterase (PDE) inhibitors (such as milrinone) and Ca2+ sensitizers (levosimendan). The mechanisms of action of these drugs, and important issues regarding their clinical indications and potential risks associated with their use are studied. Oral inotropes did not always improve mortality of the patients with heart failure (HF) partly because of possible direct toxic effects of these agents on myocytes, exacerbating arrhythmias, enhancing neurohormonal activity. Ca2+ sensitizers such as pimobendan and levosimendan were improve even mortality of the patients with HF through increasing cardiac contractility (CC) without a rise in (Ca2+)i. However, these agents disappoint our expectations. We need the development of the agents which has more specific effect of Ca2+ sensitizing.desi adult stories
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American Journal of Medical Case Reports. 2014, 2(3), 57-74. DOI: 10.12691/ajmcr-2-3-5
Pub. Date: April 18, 2014
13281 Views5058 Downloads37 Likes
by Yavuz Yagar, Mehmet Ali Erkurt, Ilhami Berber, Ilknur Nizam, Mustafa Koroglu, Haci Bayram Berktas, Engin Burak Selcuk, Emin Kaya and Irfan Kuku
Case Report
Granulocytic sarcoma is generally associated to acute myeloblastic leukemia, either as its first clinical manifestation, tissue expression of the disease, or initial symptom of its recurrence. Less than 1 percent of patients will present with prominent extramedullary disease (i.e., myeloid sarcoma, also called granulocytic sarcoma, myeloblastoma, or chloroma). We report the case of a young patient suffering from granulocytic sarcoma of her right ankle which is symptom of its recurrence.reasons wives cheat on husbands
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American Journal of Medical Case Reports. 2014, 2(3), 55-56. DOI: 10.12691/ajmcr-2-3-4
Pub. Date: April 18, 2014
16303 Views4936 Downloads34 Likes
by Sah BP, Bhandary S, Pokharel A, Shilpakar SL, Chettri ST and Paudel D
Case Report
Supernumerary nostril is an extremely rare congenital entity which results from aberrant embryological development. The review of the literature reveals that only 31 cases of supernumerary nostril have been reported. They can be associated with other congenital anomalies. The accessory nostril may or may not communicate with the ipsilateral nasal cavity, probably depending on the degree of embryological progression of the anomaly. A case of supernumerary left nostril with no nasal cavity communication and with dermoid cyst over the right nasomaxillary groove is presented. The surgical treatment is described and the different speculative theories related to the embryogenesis of supernumerary nostrils are also reviewed.catch a cheat
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American Journal of Medical Case Reports. 2014, 2(3), 52-54. DOI: 10.12691/ajmcr-2-3-3
Pub. Date: April 14, 2014
15285 Views5856 Downloads35 Likes
by Mohammed Nasir Uddin, Mohammed Abbas Uddin Chy and Taslima Khan
Case Report
Sheehan’s syndrome is defined by varying degrees of anterior pituitary deficiency due to postpartumischemic necrosis of the pituitary gland after massive bleeding. Sheehan’s syndrome, though rare, is still one of the commonest causes of hypopituitarism in developing countries like ours. The clinical presentation is variable with abrupt or insidiously developing pituitary insufficiency after a heavy intra-partum or postpartum haemorrhage. We present an young lady with this syndrome who had slowly progressive panhypopituitarism 6 years after a severe haemorrhage associated with the delivery of a male baby.free malayalam hot sex stories
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American Journal of Medical Case Reports. 2014, 2(3), 50-51. DOI: 10.12691/ajmcr-2-3-2
Pub. Date: March 31, 2014
14013 Views4907 Downloads34 Likes
by Sujit K Prasad and Anuj Kumar Srivastava
Case Report
Carcinoma of male breast is a rare cancer in male and accounts for less than 1% of all breast cancers. Affected men are usually in their 7th or 8th decade. In a study in India 0.7% of breast carcinoma is seen in men. Predisposing factors include genetic factors, exposure to radiation and excess estrogen. High exposure to estrogen may result from excess estrogen conditions or due to androgen deficiency states.sex stories moms escort service reader
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American Journal of Medical Case Reports. 2014, 2(3), 48-49. DOI: 10.12691/ajmcr-2-3-1
Pub. Date: March 25, 2014
13237 Views4657 Downloads33 Likes