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Collapse <span class="m110 colortj mt20 fontw700">Volume 12 (2024)</span>Volume 12 (2024)
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Collapse <span class="m110 colortj mt20 fontw700">Volume 8 (2020)</span>Volume 8 (2020)
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Collapse <span class="m110 colortj mt20 fontw700">Volume 4 (2016)</span>Volume 4 (2016)
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Collapse <span class="m110 colortj mt20 fontw700">Volume 3 (2015)</span>Volume 3 (2015)
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Collapse <span class="m110 colortj mt20 fontw700">Volume 1 (2013)</span>Volume 1 (2013)
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Volume 4, Issue 3

Huge Interatrial Septum Aneurysm
Case Report
Atrial septum aneurysm (ASA) is a saccular aneurysm of the interatrial septum, bulging into either atrium during the cardiac cycle. It is mostly congenital in natures and is often associated with patent foramen ovale (PFO). ASA is increasingly gaining attention as a possible cause of cryptogenic stroke. We here present a case of ASA in an elderly female in whom ASA possibly contributed to atrial fibrillation and mitral valvular prolapse; she denied any thromboembolic event. Transesophageal echocardiography remains the imaging modality of choice for diagnosis of ASA. Management guidelines for initiation of antiplatelet therapy, anticoagulation and the need for endovascular or surgical closure of associated PFO are lacking.
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American Journal of Medical Case Reports. 2016, 4(3), 111-114. DOI: 10.12691/ajmcr-4-3-10
Pub. Date: April 18, 2016
18125 Views5043 Downloads
Diagnosis of the Combination of Immune Thrombocytopenia and Woodhouse-Sakati Syndrome
Case Report
Woodhouse-Sakati Syndrome (WSS) is a rare autosomal recessive syndrome characterized by sensorineural hearing loss, ECG ST-T changes, partial alopecia, hypogonadism, diabetes, and moderate mental retardation. A 23-year-old male patient was admitted to our hospital with complaints of purpura and petechial rashes. His platelet count was 3.04 x 109/L and the peripheral blood smear was compatible with this count. No atypical cell was observed. He had mild mental retardation. He had hearing loss since childhood. Physical examination showed widespread petechiae and purpura on bilateral lower extremities. Significant growth retardation was detected and male pattern hair growth was less. In genital examination, bilateral testicles were small; penis length was 1 cm and it was 4 cm when elongated. T negativity was present in precordial derivations of ECG. He was diagnosed Immune thrombocytopenic purpura (ITP) and WSS according to these findings. In addition to ITP treatment with steroids, the combination of testosterone propionate and testosterone phenyl propionatewas also administered to him. Upon we observed that there was an increase in his platelet number, he was discharged from the hospital. WSS is a very rare disease. Different components of the syndrome have been reported in different patients.It is the first time in the literature that ITP is observedtogether with WSS in a male patient.
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American Journal of Medical Case Reports. 2016, 4(3), 108-110. DOI: 10.12691/ajmcr-4-3-9
Pub. Date: April 15, 2016
10442 Views3125 Downloads2 Likes
Pulmonary Adenofibroma; A Rare Finding
Case Study
Pulmonary adenofibroma is a rare lung benign tumor resembling adenofibroma of the breast and genital tract. Few cases have been reported with this entity. We report a case of pulmonary adenofibroma in a 65-year-old female, which was found incidentally through the work up for her gastrointestinal problems. Chest radiograph and computed tomography scan disclosed a well circumscribed pulmonary mass at left lower lung lobe. Surgical excision was done and the specimen studied macroscopically and microscopically. Histological findings revealed a biphasic lesion showing a leaflike fibroepithelial pattern with stromal and epithelial components. Immunohistochemical studies showed positivity for pan cytokeratin (CK), CD34, vimentin, smooth muscle actin (SMA), but negative for S100 and calretinin. The patient had neither symptoms nor recurrence through one and half year follows up.
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American Journal of Medical Case Reports. 2016, 4(3), 101-107. DOI: 10.12691/ajmcr-4-3-8
Pub. Date: April 14, 2016
17902 Views3382 Downloads20 Likes
Isolated Dislocation of Ocular Lens
Case Report
We describe a case of a child whit isolated dislocated of ocular lens, due to mutation in FBN1 gene. Differential syndromic diagnosis is made and we discuss to importance of clinical follow-up to exclude/confirm cardiologic complications due to Marfan syndrome.
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American Journal of Medical Case Reports. 2016, 4(3), 97-100. DOI: 10.12691/ajmcr-4-3-7
Pub. Date: April 13, 2016
11411 Views3001 Downloads
Recurrent Cardio-embolic Cerebrovascular Accidents due to Lambl’s Excrescences?
Original Research
Cerebrovascular accidents (strokes) are leading cause of morbidity and mortality in the United States of America. Cardioembolic strokes account for one-third of cerebrovascular accidents. Lambl’s excrescences are filiform projections on the native cardiac valves; they are attributed as a rare cause of cardioembolic strokes. They are a result of endothelial damage secondary to valve wear and tear. Lambl’s excrescences as a cause of cardioembolic stroke is debated. Lambl’s excrescences are a frequent appearance on echocardiography. We here present a case of recurrent cardioembolic strokes in whom lambl’s excrescences on aortic valves were detected on transesophageal echocardiography. Previous transthoracic echocardiography in the patient had not revealed lambl’s excrescences owing to their low sensitivity. Patient refused aortic valve replacement and medical management of cerebrovascular accident was continued.
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American Journal of Medical Case Reports. 2016, 4(3), 93-96. DOI: 10.12691/ajmcr-4-3-6
Pub. Date: April 12, 2016
14950 Views4060 Downloads
Sigmoid Diverticulitis: A Rare Complication of Colovaginoplasty
Case Report
Colovaginoplasty is a surgical technique using a segment of the colon along its vascular pedicle to form neovagina and its lining. This surgery is usually performed on women with androgen insensitivity syndrome, congenital adrenal hyperplasia, vaginal agenesis, müllerian agenesis, and in sex reassignment surgery. We report a case sigmoid diverticulitis in a 64 years old female with history of colovaginoplasty transgender surgery using sigmoid colon. The literature is reviewed, and MRI imaging findings are highlighted.
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American Journal of Medical Case Reports. 2016, 4(3), 91-92. DOI: 10.12691/ajmcr-4-3-5
Pub. Date: April 07, 2016
11885 Views2952 Downloads1 Likes
A Case of Necrotic and Ulcerative Skin Lesions
Case Report
A 69 year old Caucasian female smoker with an unremarkable past medical history presenting with diffusing necrotic and ulcerative skin lesions of unknown etiology. After an extensive workup, the diagnosis of calciphylaxis sine calcifications was made following results from laboratory and biopsy results.
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American Journal of Medical Case Reports. 2016, 4(3), 87-90. DOI: 10.12691/ajmcr-4-3-4
Pub. Date: March 26, 2016
12063 Views2370 Downloads
Breaking It Gently: A Rare Case of Arrhythmogenic Right Ventricular Cardiomyopathy Presenting as Sustained Ventricular Tachycardia
Case Report
We report a case of a 42-year-old female with Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) who presented with recurrent episodes of palpitations, dizziness and lightheadedness. On evaluation, she developed a new onset sustained ventricular tachycardia (VT) and the diagnosis was confirmed through genetic testing, cardiac imaging, and electrophysiological study. Insertion of automatic implantable cardioverter defibrillator (AICD), antiarrhythmic medication, and ventricular ectopy radiofrequency ablation afforded improvement of symptoms. In conclusion, combination of these treatment modalities abated ventricular tachycardia from ARVC.
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American Journal of Medical Case Reports. 2016, 4(3), 83-86. DOI: 10.12691/ajmcr-4-3-3
Pub. Date: March 25, 2016
9477 Views4104 Downloads25 Likes
Lafora Body Disease: A Rare Type of Progressive Myoclonic Epilepsy
Case Report
Lafora body disease is one of the inherited progressive myoclonic epilepsy (PME) syndromes. It is an autosomal-recessive disorder with onset in late childhood or early adolescence. The disease is characterized by fragmentary, symmetric, or generalized myoclonic and/or generalized tonic-clonic seizures, visual hallucinations (occipital seizures), and progressive neurologic degeneration including cognitive and/or behavioral deterioration, dysarthria, and ataxia. The frequency and intractability of seizures increase over time. Status epilepticus is common. Emotional disturbance and confusion are common at or soon after onset of seizures and are followed by dementia. Dysarthria and ataxia appear early, spasticity late. Pathologically polyglucosan inclusion bodies (Lafora body) are seen which are pathognomonic of the disease and are not seen in any other types of PMEs. Electroencephalogram (EEG) reveals slowing of background and generalized spike/polyspike-and-waves and photosensitivity. Most affected individuals die within ten years of onset, usually from status epilepticus or from complications related to nervous system degeneration.
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American Journal of Medical Case Reports. 2016, 4(3), 80-82. DOI: 10.12691/ajmcr-4-3-2
Pub. Date: March 24, 2016
13598 Views4609 Downloads2 Likes
Hemophagocytic Lymphohistiocytosis (HLH): A Case Series and Review
Case Study
Background Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening emergency and any delay in diagnosis and/or treatment is associated with high mortality. It is rarely observed in adult patients. HLH has multifaceted clinical presentations with often non-specific signs and symptoms that are often found in other clinical conditions. Classical manifestations suggestive of HLH include fever, cytopenia (thrombocytopenia), liver dysfunction, presence of CNS symptoms and coagulopathy. Hepatic dysfunction and failure can also be a presenting manifestation of HLH and may greatly complicate the clinical course. Case Presentation: We present four cases of secondary HLH in adults with varying presentations with a variety of underlying triggers including EBV infection, T cell lymphoma and blinatumomab therapy. Conclusion: HLH has multifaceted clinical presentations with often non-specific signs and symptoms that are often found in other clinical conditions. Early recognition of HLH is critical in initiating therapy early on and preventing high mortality resulting from multi-organ failure.
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American Journal of Medical Case Reports. 2016, 4(3), 74-79. DOI: 10.12691/ajmcr-4-3-1
Pub. Date: March 23, 2016
22128 Views4579 Downloads