by Hossain Ibrahim Ageel, Ghadah Mtaen Gosadi and Adeeb Ali Ageel
Case Report
Congenital Glucose-Galactose Malabsorption (GGM) is a rare inherited disease due to defects in the sodium-glucose cotransporter (SGLT1). It carries high morbidity and mortality if not recognized and treated early. Patients with GGM usually present with severe, life-threatening diarrhea and dehydration from neonatal period. The only treatment is to eliminate the glucose and galactose from the diet. Association of GGM with another inherited disease is unusual and rarely described in the literature. Here, we report a Saudi boy presented at one month of age with a history of chronic watery diarrhea since birth complicated with hypernatremic dehydration, and eventually, we diagnosed him as GGM. He has hypopigmented skin, hair, and eyes with bilateral nystagmus consistent with oculocutaneous albinism (OCA). As far as we know this is the first reported case worldwide of having both GGM and OCA in the same patient. It alerts the pediatricians to this association during their approach for these cases.
American Journal of Medical Case Reports. 2017, 5(6), 171-173. DOI: 10.12691/ajmcr-5-6-10
Pub. Date: July 15, 2017
8024 Views2062 Downloads14 Likes
by Mohamad Qoreishy, Ali Keipourfard, Alireza Manafi Rasi, Ali Tahririan and Mehran Soleyman Ha
Original Research
Background: Internal fixations for olecranon fractures, like tension band wiring and plates, have some complications such as prominence of the devices, neurovascular injuries, superficial infection, and skin irritation. In this study, a new triceps aponeurosis tongue shape flap technique was used to solve the problem in patients with olecranon fracture fixation.Materials and methods: Nine patients with olecranon fractures were evaluated. After fixation by tension band wiring and plate, the free aponeurosis triceps muscle in a tongue-shaped flap was used and rotated 180° to cover the whole the pin wire or plate. The surgeon then began to suture it to the anconeus, extensor carpi ulnaris and flexor carpi ulnaris muscles, fully around, with absorbable sutures. The follow-up time was eight weeks and a Mayo elbow performance score (MEPS) was filled for all patients. Results: Nine patients were analysed. Two cases were male and seven was female. The meanage was 49.11±10.37 years. Extension was full in six patients and was 170 in three. Flexion was full in all patients. No complications were recorded. The MEPS results showed that it was good and excellent in all the patients (number for patients was in the range of 80-95).Conclusion: According to results of present study, this technique can help to surgical fixation of olecranon fractures with different devices to have fewer complications, especially prominence of fixator systems and with this method tension band wiring can be remained as a gold standard in olecranon fracture fixation.
American Journal of Medical Case Reports. 2017, 5(6), 166-170. DOI: 10.12691/ajmcr-5-6-9
Pub. Date: July 15, 2017
6765 Views2279 Downloads1 Likes
by Ali Akbar Esmailiejah, Mohamad Qoreishy, Ali Keipourfard and Shahrzad Babaei
Original Research
Objective: A prospective study of several radiographic parameters of sagittal profile of the spine was conducted to determine the clinical values of these parameters. Methods: The lumbar lordotic curve was measured as Lumbar Lordotic Angle (LLA), Lumbosacral Angle (LSA), Sacral Horizontal Angle (SHA) and our suggested new parameter, Lumbar Sagittal Balance Axis (LSBA). We compared the association between LLA, LSA, SHA and LSBA in 100 patients with chronic low back pain (LBP) and 100 control group. Results: LSA was statistically significant in male ones in patients and control group (P=0.0001) but this angle didn’t showed a significant difference without the effect of gender. SHA angle didn’t show any statistical significance in patients with LBP. A significant correlation was observed between LSBA increase and LBP (P=0.001).Conclusion: Measurement of LSAs and LSBAs may provide orthopedic surgeons some appropriate parameters to predict acute to chronic LBP transformation risks.
American Journal of Medical Case Reports. 2017, 5(6), 163-165. DOI: 10.12691/ajmcr-5-6-8
Pub. Date: July 15, 2017
11241 Views3043 Downloads1 Likes
by Tariq Al-Debasi, Mohammed K. Khuthaila, Abdulmajeed S. Al-Fakhri, Yazeed A. Al-Ferayan, Rabia Bashir, Abdulmalik Abbasi, Abdulmalik M. Alkatheri and Abdulkareem M. Al Bekairy
Case Report
We report a paediatric idiopathic thrombocytopenia purpura (ITP) patient with primary spontaneous suprachoroidal haemorrhage (SSCH). The patient was diagnosed of ITP based on platelets count and morphology. Eye ultrasound indicated SSCH with total choroidal detachment. After improvement of the patient platelet count using immunoglobulin treatment, two surgical vitrectomy were performed on the patient with 3-weeks interval. After six months-follow up, the patient revealed normal IOP and hand motion vision in the left eye. We recommend that ITP should be considered as one of the risk factors for vision threatening ocular haemorrhages even for paediatric patients.
American Journal of Medical Case Reports. 2017, 5(6), 156-159. DOI: 10.12691/ajmcr-5-6-6
Pub. Date: July 12, 2017
6670 Views2264 Downloads1 Likes
by Nicoli Taiana Henn, Julia Pastorello and Marina Ractz Bueno
Case Report
Immunotherapies are new drugs that are revolutionizing the treatment of many malignancies, among them, the kidney cancer. Because of their mechanism of action they can trigger an important inflammatory responses and immune-mediated adverse events. The safety of influenza vaccination during the use of checkpoint inhibitors is not defined. We report the case of a patient with kidney cancer who evolved unfavorably a few days after receiving the influenza immunization without the consent of the oncology specialists.
American Journal of Medical Case Reports. 2017, 5(6), 151-155. DOI: 10.12691/ajmcr-5-6-5
Pub. Date: July 08, 2017
10975 Views2398 Downloads1 Likes
by Waleed AL Ruziaki and Hilal AL Hashami
Case Report
Comamonas testosteroni initially has been considered as a nonpathogenic microorganism until 1987; after which year, it has being recognized as a human pathogen with spectrum of infections both in adult and children. We report the first case of a healthy child who is 12 months old Omani girl presented with features of acute gastroenteritis with Comamonas testosteroni sepsis, that was treated successfully with two weeks course of intravenous ceftriaxone with excellent outcome. Most of the reported cases of Comamonas testosterone infection were sensitive to antibiotics with favorable outcome.
American Journal of Medical Case Reports. 2017, 5(6), 148-150. DOI: 10.12691/ajmcr-5-6-4
Pub. Date: July 04, 2017
9654 Views2751 Downloads1 Likes
by Mohammed Ali Tohary, Hassan Mohammed Gohal, Ali Abdullah Awaji, Ali Abdullah Kamli and Hossain Ibrahim Ageel
Case Report
Acute pancreatitis (AP) has rarely been reported in association with pediatric Henoch-Schonlein purpura (HSP) and even very occasionally reported as a primary clinical feature presenting before the development of characteristic palpable purpura. We describe here a five years and six months old girl presented with acute pancreatitis in the form of focal groove pancreatitis. The characteristic rash of HSP developed later in the disease course. This rare entity is discussed to alert pediatricians to include acute pancreatitis in the differential diagnosis of abdominal pain complicating HSP.
American Journal of Medical Case Reports. 2017, 5(6), 144-147. DOI: 10.12691/ajmcr-5-6-3
Pub. Date: July 03, 2017
9266 Views2069 Downloads11 Likes
by Melike Elif Teker
Case Report
Aortic coarctation is a congenital cardiac disease which is typically diagnosed and treated in childhood. If left untreated, aortic coarctation may lead to complications such as myocardial infarction, aortic aneurysm, aortic dissection and intracranial hemorrhage. In this study, we aimed to present the combined surgical and endovascular method that we performed in a 32-year-old male patient who had hypoplastic aortic arch, aortic coarctation and aortic aneurysm starting from the proximal left subclavian artery.
American Journal of Medical Case Reports. 2017, 5(6), 141-143. DOI: 10.12691/ajmcr-5-6-2
Pub. Date: July 01, 2017
9438 Views2154 Downloads1 Likes
by Yanardag H, Tetikkurt C, Bilir M, Kepil N and Verdi Y
Case Report
Sarcoidosis is a multisystemic granulomatous disease characterised by the histologic evidence of granulomas in various organs. Clinically discernible gastric sarcoidosis is extremely rare, reported in less than 1% of the patients. We present a case of gastric sarcoidosis with atypicial manifestations and without current pulmonary disease. The patient was admitted for gastric fullness, anorexia, and weight loss. She had a history of migraine and nodular goiter. Family history revealed bladder carcinoma in the mother and gastric carcinoma in the uncle. Initial laboratory findings and chest x-ray were normal. Biopsies from the gastric mucosa revealed noncaseating granulomas with focal multinucleate giant cells. Six months after the patient was admitted for dry cough and fatigue. Chest x-ray and CT revealed diffuse nodules in the upper and middle lung zones. Transbronchial biopsy demonstrated noncaseiting granulomas compatible with sarcoidosis. The patient was started on mehtylprednisolone and had a significant improvement in her symptoms. This case is an unique paradigm for the exceptional presentation of sarcoidosis. Isolated extrapulmonary organ involvement without simultaneous lung disease may be the initial manifestation of sarcoidosis. Meticulous follow-up for sarcoidosis is required for patients presenting with atypical symptoms and noncaseiting granulomas in any extrapulmonary organ.
American Journal of Medical Case Reports. 2017, 5(6), 135-140. DOI: 10.12691/ajmcr-5-6-1
Pub. Date: June 27, 2017
13921 Views3347 Downloads1 Likes