by Hossain Ibrahim Ageel and Marwah Ali Al-Agsam
Case Report
Several reports described nephrolithiasis and nephrocalcinosis in children with glucose-galactose malabsorption (GGM). The etiology of renal stones in GGM is not known, but the chronic dehydration and concentrated urine complicating chronic diarrhea in GGM might be a possible mechanism. Few reports described nephrocalcinosis in association with hypercalcemia, hypercalciuria, and renal tubular defect. Both nephrolithiasis and nephrocalcinosis can present in the neonatal period at the time of diagnosis or manifest later during follow up. We are aware of eleven patients of GGM with nephrolithiasis reported worldwide, and eight patients of GGM with nephrocalcinosis. In this current report, we describe a total of five patients with GGM complicated with nephrolithiasis (three cases), and nephrocalcinosis (two cases). As far as we know, this series is the largest group of patients described with these complications in one report. We aim from this paper to deliver a message to the pediatricians and pediatric gastroenterologist to do regular ultrasonography of the kidneys in all patients of GGM at the time of diagnosis and during follow up to recognize these complications early and refer them in the right moment for management.
American Journal of Medical Case Reports. 2017, 5(7), 190-195. DOI: 10.12691/ajmcr-5-7-6
Pub. Date: August 08, 2017
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by Ozan Akinci, Serhat Sirekbasan, Murat Toksoy and Sefa Ergun
Case Report
Myiasis is a parasitic infection that occurs as a result of larvae, settling in living tissues and organs, observed especially in tropical regions and rural areas where animal contact is common. Diagnosis is established by observing larvae of Diptera species in tissues and organs. In treatment planning, determining the type of larvae as well as affected organ and systems is important in terms of treatment and follow up. In this case report, we discussed a female patient with ulcerated mass in the right breast in whom Lucilia cuprina larvae caused myiasis after a holiday in the summer in a village.
American Journal of Medical Case Reports. 2017, 5(7), 196-198. DOI: 10.12691/ajmcr-5-7-7
Pub. Date: August 11, 2017
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by Dhayhi Nabil S., Arishi Haider M., Alnami Mohammed Y. and Dammur Prabhara
Original Research
Sickle cell anemia (SCA ) is one of the most common hemoglobinopathies, which is characterized by a high level of abnormal hemoglobin called hemoglobin S (Hb S). This abnormal hemoglobin results from changes in amino acids and valine instead of glutamine at the sixth position of the β globin molecule. Two affected genes are needed to develop sickle cell anemia, homozygous Hb S.
American Journal of Medical Case Reports. 2017, 5(7), 187-189. DOI: 10.12691/ajmcr-5-7-5
Pub. Date: August 07, 2017
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by Abu Marar E and Al-Hasani S
Original Research
Since decades back, specifically since the development of infertility treatment was progressively advancing, the multiple pregnancy is increasing drastically and of the major contributors to this increment is assisted reproductive technology ART, which reflects an increased risk for both mother and fetus other than being a health hazard. We reviewed the literature systematically to explore and compare the dual embryo transfer DET with single embryo transfer SET weather electively or not in more viewpoints like financially, and scientifically and finding out which of these policies may give better outcome by analyzing both in a neutral broad spectrum manner. Our results were given upon some clinical trials, and in part upon other articles found in the literature, but the comparison between all these articles found to be unreliable due to the huge variation between them all, ending up finally that SET has the advantage of minimizing the twinning and multiple pregnancy rate MPR. On the other hand SET has less benefit when compared to DET in the matter of implantation rate IR, ongoing pregnancy rate OPR, but a comparable results may be obtained when applying elective single embryo transfer eSET of frozen-thawed embryo. We concluded that larger clinical trials should still be encouraged for such comparison especially in applying same criteria for both methods.
American Journal of Medical Case Reports. 2017, 5(7), 181-186. DOI: 10.12691/ajmcr-5-7-4
Pub. Date: August 01, 2017
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by Luqman Salahudeen, Paulisa Ward, Rekha Kumari, Efemena Diejomaoh, Vel Sivapalan and Simona Bratu
Case Report
Raoultella planticola is a gram-negative aerobic bacillus commonly found in water, plant and soil. Few cases have been reported of this organism affecting humans. We present the case of 68-year-old woman with a five-day history of inability to move right hand. Physical examination revealed an erythematous fluctuant swelling which was incised and drained. Drainage specimen was cultured and grew Raoultella planticolasusceptible to augmented penicillin’s. Patient achieved significant clinical improvement following treatment with ampicillin-sublactam. Clinicians should be aware of this emerging pathogen as a cause of soft tissue infection in humans.
American Journal of Medical Case Reports. 2017, 5(7), 179-180. DOI: 10.12691/ajmcr-5-7-3
Pub. Date: August 01, 2017
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by P. Srivastava, B. Jacob, A. Challa, M. Loya, C. Stadler, K. Rizvon, N. Khan, J. Akella, W. Chua, J. Iqbal and P. Mustacchia
Case Report
Pancreaticopleural fistulas are a rare complication of acute or chronic pancreatitis, pancreatic trauma, or complicated pancreatic pseudocyst rupture. It accounts for less than 1% of all cases resulting in pleural effusions and is seen in approximately 7% of patients with chronic pancreatitis and in 14% of patients with pseudocyst. Persistent pancreatic secretions result in erosion of neighboring tissue. Left sided effusions are more common than right sided effusion, accounting up to 76%. Pathophysiology incompletely formed or ruptured pseudocyst. The fistulous tract passes either through the sternocostal triangle, the caval hiatus or directly through the defects aortic or esophageal diaphragmatic orifice. If the pancreatic duct disruption occurs anteriorly, a pancreaticoperitoneal fistula will develop that will manifest as ascites. If the disruption develops posteriorly, pancreatic secretion will flow into retroperitoneum and may dissect through the diaphragm into mediastinum and form a pleural fistula or present as mediastinal pseudocyst. We present a case of a large bilateral pleural effusion secondary to a pancreaticopleural fistula in a patient with multiple risk factors.
American Journal of Medical Case Reports. 2017, 5(7), 177-178. DOI: 10.12691/ajmcr-5-7-2
Pub. Date: July 31, 2017
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by Yong Kuei Lim
Case Report
Background: Obturator nerve injury is a rare complication and it may occur during pelvic cancer surgery especially during pelvic lymphadenectomy. The injury may cause paraesthesia, sensory loss or pain in the medial thigh which may extend down to the knee. It can also cause weakness in adduction with gait disturbance, medial thigh wasting and possible medico-legal consequences. Case Report: The patient is a 57 year old lady who was found to have an early cervical cancer. MRI abdomen and pelvis was negative for regional lymphadenopathy or distant metastases hence clinically she had a Stage IB1 SCC of cervix. She underwent a Total Laparoscopic Wertheim's Radical Hysterectomy BSO Bilateral Pelvic Lymphadenectomy in February 2015. During the pelvic lymphadenectomy, the left obturator nerve was inadvertently damaged and partially transected by the Harmonic scalpel. The nerve was reconstituted by interrupted 5-O vicryl suture to the epineural layer of the nerve. Post operatively, the patient experienced weakness of the adductor muscles (3/5) but negligible sensory loss. Four months after intensive physiotherapy, the motor deficit was markedly reduced and her gait was normal. There was no sensory loss. Final histology revealed that the surgical margins was clear and 0/41 pelvic lymph nodes were negative. Hence she did not need any adjuvant therapy. Conclusion: Obturator nerve injury is a rare complication with a significant clinical impact if unrecognised. In uncomplicated cases, laparoscopic route of repair is feasible and safe and an immediate repair of the nerve is preferable.
American Journal of Medical Case Reports. 2017, 5(7), 174-176. DOI: 10.12691/ajmcr-5-7-1
Pub. Date: July 26, 2017
11607 Views2974 Downloads2 Likes