Skip Navigation Links.
Collapse <span class="m110 colortj mt20 fontw700">Volume 12 (2024)</span>Volume 12 (2024)
Collapse <span class="m110 colortj mt20 fontw700">Volume 11 (2023)</span>Volume 11 (2023)
Collapse <span class="m110 colortj mt20 fontw700">Volume 10 (2022)</span>Volume 10 (2022)
Collapse <span class="m110 colortj mt20 fontw700">Volume 9 (2021)</span>Volume 9 (2021)
Collapse <span class="m110 colortj mt20 fontw700">Volume 8 (2020)</span>Volume 8 (2020)
Collapse <span class="m110 colortj mt20 fontw700">Volume 7 (2019)</span>Volume 7 (2019)
Collapse <span class="m110 colortj mt20 fontw700">Volume 6 (2018)</span>Volume 6 (2018)
Collapse <span class="m110 colortj mt20 fontw700">Volume 5 (2017)</span>Volume 5 (2017)
Collapse <span class="m110 colortj mt20 fontw700">Volume 4 (2016)</span>Volume 4 (2016)
Collapse <span class="m110 colortj mt20 fontw700">Volume 3 (2015)</span>Volume 3 (2015)
Collapse <span class="m110 colortj mt20 fontw700">Volume 2 (2014)</span>Volume 2 (2014)
Collapse <span class="m110 colortj mt20 fontw700">Volume 1 (2013)</span>Volume 1 (2013)
American Journal of Medical Case Reports. 2022, 10(9), 230-234
DOI: 10.12691/AJMCR-10-9-5
Case Report

Cerebral Venous Sinus Thrombosis as a Rare Complication of Hyperemesis Gravidarum: A Case Report

Oadi N. Shrateh1, , Hashem M. Khdour1, Duha Y. Jawaada2, Haneen Owienah3, Thaer Sweileh3, Samer Barahmeh4 and Ahmad Al-Sarahneh2

1Faculty of Medicine, Al-Quds University, Jerusalem, Palestine

2Department of Obstetrics and Gynecology, AL-Makassed Charitable Society Hospital, East Jerusalem, Palestine

3Radiology Department, Al-Istishari Arab Hospital, Ramallah, West Bank, Palestine

4Department of Obstetrics and Gynecology, Al-Istishari Arab Hospital, Ramallah, Palestine

Pub. Date: September 18, 2022

Cite this paper

Oadi N. Shrateh, Hashem M. Khdour, Duha Y. Jawaada, Haneen Owienah, Thaer Sweileh, Samer Barahmeh and Ahmad Al-Sarahneh. Cerebral Venous Sinus Thrombosis as a Rare Complication of Hyperemesis Gravidarum: A Case Report. American Journal of Medical Case Reports. 2022; 10(9):230-234. doi: 10.12691/AJMCR-10-9-5

Abstract

Objective: Cerebral venous sinus thrombosis (CVST) is an uncommon but serious sequalae of severe hyperemesis gravidarum. Pregnancy and puerperium are important risk factors for CVST. Here, we report a case of CVST induced by hyperemesis gravidarum. Case report: A 25-year-old Palestinian woman, gravida 3, para 2 in the first trimester of her pregnancy. The patient was first diagnosed with severe hyperemesis gravidarum due to recurrent episodes of nausea and vomiting. As the condition advanced, the patient had headache and generalized weakness for a one-week duration. Neuroimaging revealed extensive thrombosis in the cerebral sinuses; thereby CVST was diagnosed. The patient was treated with anticoagulant and had a complete recovery. Conclusion: Although rare, it is important to include cerebral venous sinus thrombosis (CVST) in the differential diagnosis of any brain syndrome during all trimesters of pregnancy and puerperium. In this case study, we affirm the significance of suspecting CVST in pregnant women complaining of any neurological syndrome, especially in the setting of severe hyperemesis gravidarum.

Keywords

cerebral venous sins thrombosis, severe hyperemesis gravidarum, pregnancy, puerperium, neuroimaging, anticoagulation

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]  Saposnik G, Barinagarrementeria F, Brown Jr RD, Bushnell CD, Cucchiara B, Cushman M, Deveber G, Ferro JM, Tsai FY. “Diagnosis and management of cerebral venous thrombosis: a statement for healthcare professionals from the American Heart Association/American Stroke Association”. Stroke.; 42(4): 1158-92. Apr 2011.
 
[2]  Cantu C, Barinagarrementeria F. “Cerebral venous thrombosis associated with pregnancy and puerperium. Review of 67 cases”. Stroke.; 24(12): 1880-4. Dec 1993.
 
[3]  Bousser, M.-G. and J.M. Ferro, “Cerebral venous thrombosis: an update”. The Lancet Neurology. 6(2): p. 162-170. Feb 2007.
 
[4]  Lim, Y., “Aseptic cerebral venous sinus thrombosis in early pregnancy”. Hong Kong Journal of Emergency Medicine. 14(4): p. 237-239. Oct 2007.
 
[5]  Duman T, Uluduz D, Midi I, Bektas H, Kablan Y, Goksel BK, Milanlioglu A, Orken DN, Aluclu U, Colakoglu S, Tüfekci A. “A multicenter study of 1144 patients with cerebral venous thrombosis: the VENOST study”. Journal of Stroke and Cerebrovascular Diseases. 1; 26(8): 1848-57. Aug 2017.
 
[6]  Sharma, N., S.R. Sharma, and M. Hussain, “An audit of cerebral venous thrombosis associated with pregnancy and puerperium in teaching hospital in North Eastern India”. Journal of Family Medicine and Primary Care. 8(3): p. 1054. Mar 2019.
 
[7]  Ferro JM, Canhão P, Stam J, Bousser MG, Barinagarrementeria F. “Prognosis of cerebral vein and dural sinus thrombosis: results of the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT)”. Stroke. 1;35(3): 664-70. Mar 2004.
 
[8]  Edlow JA, Caplan LR, O'Brien K, Tibbles CD. “Diagnosis of acute neurological emergencies in pregnant and post-partum women”. The Lancet Neurology. 1; 12(2): 175-85. Feb 2013.
 
[9]  Canhão P, Abreu LF, Ferro JM, Stam J, Bousser MG, Barinagarrementeria F, Fukujima MM, ISCVT Investigators. “Safety of lumbar puncture in patients with cerebral venous thrombosis”. European Journal of Neurology.; 20(7): 1075-80. Jul 2013.
 
[10]  Negro A, Delaruelle Z, Ivanova TA, Khan S, Ornello R, Raffaelli B, Terrin A, Reuter U, Mitsikostas DD. “Headache and pregnancy: a systematic review”. The journal of headache and pain.;18(1):1-20. Dec 2017.
 
[11]  Dentali F, Squizzato A, Marchesi C, Bonzini M, Ferro JM, Ageno W. “D-dimer testing in the diagnosis of cerebral vein thrombosis: a systematic review and a meta-analysis of the literature”. Journal of thrombosis and haemostasis.; 10(4): 582-9. Apr 2012.
 
[12]  van Dam LF, van Walderveen MA, Kroft LJ, Kruyt ND, Wermer MJ, van Osch MJ, Huisman MV, Klok FA. “Current imaging modalities for diagnosing cerebral vein thrombosis–A critical review”. Thrombosis research. 1; 189:132-9. May 2020.
 
[13]  Tanislav C, Siekmann R, Sieweke N, Allendörfer J, Pabst W, Kaps M, Stolz E. “Cerebral vein thrombosis: clinical manifestation and diagnosis”. BMC neurology.; 11(1): 1-5. Dec 2011.
 
[14]  Ferro JM, Canhão P, de Sousa DA. “Cerebral venous thrombosis”. La Presse Médicale. 1;45(12): e429-50. Dec 2016.
 
[15]  Allroggen H, Abbott RJ. “Cerebral venous sinus thrombosis”. Postgraduate medical journal. 1;76(891): 12-5. Jan 2000.