by Su Hyun Jeong, Nishitha Shekhar, Matthew Amin, Amir Nabizadeh and Neelesh Mutyala
Case Report
We report a case of Adult-onset Still’s Disease (AoSD) in a 55-year-old male without prior rheumatological history. The disease is an autoinflammatory condition with features including fevers, joint pain, and salmon-colored lesions. Diagnosis is through clinical classification systems including the Yamaguchi or Fautrel criteria and considered after a thorough diagnosis of exclusion. However, the disease is rare and difficult to recognize given its nonspecific presentation. This patient depicts the challenges in noticing the disease, especially in the setting of confounding physical exam findings. Prognosis is favorable, but prolonged periods without treatment can lead to the development of harmful complications including fulminant hepatitis, lymphohistiocytic activation syndrome, and disseminated intravascular coagulation.
American Journal of Medical Case Reports. 2023, 11(12), 172-175. DOI: 10.12691/ajmcr-11-12-2
Pub. Date: December 11, 2023
by Mohammed Aboelnaga, Mahfoud El. Bashari, Amani Alzaabi and Hesham Eissa
Case Study
Despite being uncommon, thrombotic complications from COVID-19 vaccinations that cause cerebrovascular events have been extensively studied. Moyamoya angiopathy (MMA) is a progressive intracranial vasculopathy that is responsible for causing recurrent strokes. This report analyzes a case of cerebrovascular stroke post-COVID-19 vaccination (inactivated-Sinovac) in a middle-aged Asian female. The patient was administered two doses of Sinovac, followed by one dose of the Pfizer vaccine, which led to the diagnosis of Moyamoya disease. The report aims to study MMA in a patient exhibiting exacerbated symptoms post-vaccination, thereby forming a basis for research regarding the safety of COVID-19 vaccinations in patients with pre-existing intracranial vasculopathy. Although such a correlation may not necessarily imply causality, caution must be exercised till future robust observations are obtained, especially considering the possibility of a shared inflammatory pathophysiological foundation between MMA and COVID-19 vaccinations.
American Journal of Medical Case Reports. 2023, 11(12), 169-171. DOI: 10.12691/ajmcr-11-12-1
Pub. Date: December 06, 2023
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