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Volume 12, Issue 1

Idiosyncratic LDH Elevation in a Young and Healthy Female Patient, a Case of Macro-LDH Detection Using PEG Precipitation
Case Report
Lactate dehydrogenase (LDH) is an unspecific marker predominantly for hemolysis, thrombotic, infectious, and malignant diseases. On rare occasions, it can also be idiosyncratically elevated. We present a case of a 30-year-old otherwise healthy female patient who is referred to outpatient internal medicine with a persistent LDH elevation for years. Extensive laboratory and radiological diagnostics are performed without any indications of disease. Macro-LDH is suspected, and serum immunocomplex precipitation with polyethylene glycol is performed. Laboratory results make the presence of macro-LDH likely. Therefore, it is suggested that macroenzymes be considered early in the diagnostic journeys of patients with elevated serum enzyme activities unsuitable to the corresponding clinical context to spare them unnecessary procedures and provide them with a diagnosis of this probable benign condition.
American Journal of Medical Case Reports. 2024, 12(1), 6-9. DOI: 10.12691/ajmcr-12-1-2
Pub. Date: January 29, 2024
Occlusal Rehabilitation Through Synergistic Utilization of Fixed Partial and Cast Partial Denture
Case Report
Complexity in occlusal rehabilitation lies primarily on establishing an occlusion that is in functional harmony with various components of stomatognathic complex. Patients primary objectives are aesthetic, if anterior teeth are involved and mastication, if posterior teeth are missing. The systematic and multidisciplinary approach is essential to achieve treatment goals, most of which are prosthetically driven. This article presents a case of a young Saudi female patient who reported with multiple root stumps, missing teeth and grossly decayed multiple posterior teeth. The patient was treated utilizing a combination of multiple fixed partial denture and a maxillary cast partial denture, with both arches having a Kennedy class 3 modification 1 partial edentulous situation. The pain as emergency was controlled with extraction of non restorable involved tooth and pulpal extirpation of a posterior tooth. All treatments were in multiple phases that ranged from surgical (extraction, crown lengthening, endodontic) to non surgical (oral prophylaxis, class I, II, IV restorations, post core crowns, fixed partial and cast partial denture) treatments. The patient was highly satisfied with the treatment outcome as expressed during subsequent followup.
American Journal of Medical Case Reports. 2024, 12(1), 1-5. DOI: 10.12691/ajmcr-12-1-1
Pub. Date: January 25, 2024