American Journal of Medical Case Reports

Pleomorphic adenomas are benign salivary gland tumors which represent about 3-10% of the neoplasms of head & neck region. They are the most common tumors comprising 50% of major & minor salivary gland tumors. The Palate is considered the most common (65%) and retromolar area uncommon (2.5%) intra oral site. A case of retromolar swelling diagnosed as pleomorphic adenoma of minor salivary glands is presented with review of literature of minor salivary gland tumors & pleomorphic adenoma.

American Journal of Medical Case Reports. 2014, 2(4), 90-93. DOI: 10.12691/ajmcr-2-4-6
Pub. Date: May 21, 2014

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Isolated Leprosy of Pinna Masquerading Perichondritis : A Rarest Entity

by Paudel D, Sah BP, Bhandary S, Shilpakar SL, Chettri ST and Mishra S

Case Report

Leprosy is a chronic bacterial disease caused by Mycobacterium leprae. It is the oldest known disease to human beings. Incubation period ranges from weeks to years. The prevalence of leprosy varies markedly from country to country. However, the overwhelming majority of cases are found in developing countries and 92 percent of the cases are detected in just 11 countries led by India and Brazil. Grossly leprosy is divided into lepromatous and tubercular form, based on immunological pattern of disease. Though leprosy is common condition, isolated leprosy of pinna has not been reported so far in the literature. We report a male of 15 years with clinical feature of perichondritis of left pinna due to leprosy.

American Journal of Medical Case Reports. 2014, 2(4), 87-89. DOI: 10.12691/ajmcr-2-4-5
Pub. Date: May 20, 2014

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Lacrimal Sac Rhinosporidiosis: An Unusual Case Report

by Sah BP, Chettri ST, Mishra S, Shilpakar SL, Paudel D, Kandel DR, Karki S and Devkota IR

Case Report

Rhinosporidiosis is a granulomatous disease that is a disease caused by Rhinosporidium seeberi. Though it occurs universally, the disease is widely prevalent in the tropics, especially in southern India and Sri Lanka. It usually affects the nasal mucosa and nasopharynx and rarely the conjunctiva, lacrimal sac, tonsils and skin. We present a case study of an isolated lacrimal sac rhinosporidiosis in a 15-year-old boy who was a resident of Terai. He presented with a diffuse left medial infraorbital swelling for a period of 14 months. He also complained of intermittent epiphora. External examination of the left eye revealed a diffuse, soft, and nontender swelling in the medial infraorbital region. Fine needle aspiration report was inconclusive. A computed tomography scan of the paranasal sinuses revealed an isodense lesion with mild enhancement within the preseptal compartment along the inferior aspect of the left orbit. A dacryocystectomy was performed and histopathology report confirmed rhinosporidiosis. There is no recurrence after 2 years of follow up.

American Journal of Medical Case Reports. 2014, 2(4), 84-86. DOI: 10.12691/ajmcr-2-4-4
Pub. Date: May 20, 2014

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Atypical Presentation of Plasmacytoma

by Bayram Berktaş, Mehmet Ali Erkurt, Ilhami Berber, Ilknur Nizam, Mustafa Koroglu, Engin Selcuk Burak, Yavuz Yagar, Emin Kaya and Irfan Kuku

Case Report

Plasmacytoma is a tumor seen with multiple myeloma and its localized forms are solitary bone plasmacytoma and extramedullary plasmacytoma. While the most frequent locations are vertebrae, sternum, nasopharynx, paranasal sinuses, rarely mediastinum, kidney, testis and ovary may be involved. In this case, relapsed multiple myeloma with atypical extramedullary plasmacytoma located in the frontal region is presented.

American Journal of Medical Case Reports. 2014, 2(4), 82-83. DOI: 10.12691/ajmcr-2-4-3
Pub. Date: May 14, 2014

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Chondroblastoma of the Lower Thoracic Spine. A Case Report and Review of the Literature

by Walid Osman, Afif Zaoui, Soumaya Ben Abdelkrim, Riadh Ben Hamida and Mohamed Ben Ayèche

Case Report

Background: Chondroblastoma of the spine is a very rare condition. To the best of our knowledge, fewer than 30 cases have been reported in the world literature. Material and methods: The authors describe here a rare spinal localization with an uncommon evolution and make a review of the cases of spinal chondroblastoma reported in the literature. Results: We report the case of a patient with chronic back pain and progressive weakness of both lower limbs. Computed tomography scan showed a mass infiltrating the twelfth thoracic vertebra and adjacent structures. The patient underwent surgery and subtotal removal was achieved while a posterior stabilization was performed. Pathological examination revealed a chondroblastoma. During follow-up, MRI examination revealed that the tumor had locally relapsed; nevertheless, the patient was asymptomatic for 13 years after operation. Conclusion: Spinal chondroblastoma has an aggressive behavior with high recurrence and mortality rates.

American Journal of Medical Case Reports. 2014, 2(4), 78-81. DOI: 10.12691/ajmcr-2-4-2
Pub. Date: May 14, 2014

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Hoffmann’s Syndrome a Presenting Manifestation of Hypothyroidism

by Mohammed Nasir Uddin, Abbas Uddin, Mohammed Abbas Uddin Chy and Taslima Khan

Case Report

Hypothyroidism is one of the most prevalent endocrine disorders. Different neuromuscular complications can develop with hypothyroidism. Nonspecific neuromuscular complaints like myalgia, muscle cramps and mild elevation of Creatine Kinase (CK) are the most common myopathic features related to hypothyroidism. Other myopathic features included proximal muscle weakness and myxoedema. The neurological manifestations of hypothyroidism are very unusual to see as initial symptoms and they usually occur late in the course of disease. Muscle hypertrophy is an extremely rare finding in hypothyroid patients. Hypothyroidism presenting as muscle stiffness and muscle pseudo hypertrophy in adults is known as Hoffmann's syndrome. Laboratory investigation in hypothyroid myopathy generally shows increased levels of muscle enzyme. The electrophysiological study may reveal features suggestive of myopathy, neuropathy or mixed pattern. The symptoms and also the serum levels of enzymes return to normal with hormone replacement therapy. We report a case of hypothyroidism with calf muscle hypertrophy and proximal myopathy as the initial symptoms.

American Journal of Medical Case Reports. 2014, 2(4), 75-77. DOI: 10.12691/ajmcr-2-4-1
Pub. Date: May 04, 2014

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