American Journal of Medical Case Reports

Primary splenic diffuse large B cell lymphoma is rarely clinical entity and comprises 1% of all malignant lymphomas. The spleen is also involved in immune defense against blood-borne antigens. Though the haematological malignancies, spleen is usually affected as a part of multisystemic involvement rather than isolated involvement. More than half of patients affected by Hodgkin's disease and about a third of those with non-Hodgkin lymphoma have splenic involvement. The involved spleen may be complicated with rupture due to massive splenomegaly, which may need urgent intervention. In this report, we present a 47-year-old female patient with massive splenomegaly, who was diagnosed with primary splenic diffuse large B cell lymphoma after splenectomy.

American Journal of Medical Case Reports. 2015, 3(8), 265-268. DOI: 10.12691/ajmcr-3-8-11
Pub. Date: July 28, 2015

Full-Text PDF

13487 Views3912 Downloads17 Likes

Drowning in 12-month-old Boy Who Was Later Diagnosed with Epilepsy: A Case Report and Review of Literature

by Heda Melinda Nataprawira, Nelly Amalia Risan, Yogi Agustian and Evelyn Phangkawira

Case Report

Introduction: Drowning is an event of respiratory disturbances due to submersion in water, resulting insurvival with or without complications, or death. Several risk factors for drowning are epilepsy, male, intentional accidents (neglected/abused or murdered), and lack of supervision. Objective: The aim of this study is to describe a case of drowning, with epilepsy as a risk factor. Case Presentation: A 12-month-old boy was presented due to drowning in a fish pond. He was referred from a district hospital after receiving cardiopulmonary resuscitation. There was an escalation in respiratory problems. While he was planned for discharge he had general tonic clonic seizure. After conducting electroencephalogram, he was diagnosed with epilepsy. We can’t identify whether he drowned due to lack of supervision or seizure in the pond. Conclusion: Finding a risk factor is one of the most important management in drowning. Epilepsy is one of the risk factor, which symptom is not always noticed by parents. Although denied, we still have to do rigorous anamnesis to find epilepsy until it is proven otherwise..

American Journal of Medical Case Reports. 2015, 3(8), 257-264. DOI: 10.12691/ajmcr-3-8-10
Pub. Date: July 28, 2015

Full-Text PDF

14584 Views3582 Downloads1 Likes

Kimmerle Anomaly and Drop Attacks in Adolescent

by Enrico Finale, Mauro Martinetti, Fabrizio La Rocca, Fulvio Guccione and Andrea Guala

Case Report

A. is 12 years old and comes to the first aid for a fainting spell during gym class. Pediatric and Neurological examination, ECG, EEG and RMN are all negatives. The medical history is negative regarding the main causes of Drop Attacks. Only one cervicodorsal radiography allows diagnosis of Kimmerly’s anomaly. The Kimmerly’s anomaly occurs in adults in 14% of the population, but is extremely rare in adolescents. The conduct adopted, after discussion with the neurologist and neurosurgeon, is waiting and symptoms monitoring.

American Journal of Medical Case Reports. 2015, 3(8), 255-256. DOI: 10.12691/ajmcr-3-8-9
Pub. Date: July 24, 2015

Full-Text PDF

14760 Views3835 Downloads19 Likes

A Case of Symptomatic Inflammatory Tongue Treated with Fucoidan

by Shuichi Tsubura, Yoshie Waki and Tsutomu Tsubura

Case Report

Abnormalities of symptomatic inflammatory tongue (SIT) present a diagnostic and therapeutic dilemma for clinicians. In particular, atrophic glossitis or fissured tongue is often linked to underlying semi-pathological conditions such as immunodeficiency, nutritional deficiency, or the effects of pharmacotherapy. The various therapies for this condition include corticosteroid ointment, anesthetic gel, anti-inflammatory drugs, and vitamin B12 supplementation to address the symptoms. However, none of these treatments has been evaluated rigorously. The case of an adult patient in which persistent, painful SIT was successfully treated using a 32% fucose chewable tablet is presented. In this case, PC-320^TM achieved marked improvements in SIT. Clinical trials are needed to confirm the efficacy and safety of topical PC-320 in treating SIT.

American Journal of Medical Case Reports. 2015, 3(8), 250-254. DOI: 10.12691/ajmcr-3-8-8
Pub. Date: July 23, 2015

Full-Text PDF

20652 Views6385 Downloads3 Likes

Anaplastic Large Cell Lymphoma: A Cytological Masquerade

by Sonia Chhabra, Renuka Verma, Priya Jain, Mahesh Tayal, Jagjeet Singh and Rajeev Sen

Case Report

Anaplastic large cell lymphoma accounts for less than 10% cases of all lymphomas. It is a distinct category of large cell lymphomas that shows strong expression of CD30. The reproducibility of ALCL on the morphological ground is poor and at times it may mimic other non-lymphoid malignancies. The cytomorphology of anaplastic large cell lymphoma (ALCL) is distinctive yet variable. Till date only few cases have described the cytologic findings of ALCL. We here present a case of ALCL who presented to us with cervical lymphadenopathy and high grade fever.

American Journal of Medical Case Reports. 2015, 3(8), 247-249. DOI: 10.12691/ajmcr-3-8-7
Pub. Date: July 13, 2015

Full-Text PDF

12703 Views2881 Downloads2 Likes

Pulmonary Embolism: A Rare Initial Manifestation of Multiple Myeloma

by Parijat Sen, Abhishek Kumar, Mary Mathews, Daphne Macbruce and Richard Miller

Case Report

Multiple Myeloma usually presents with end organ damage like bone symptoms such as pain, pathologic fracture, renal dysfunction, chronic fatigue from anemia or symptoms of hypercalcemia. Although frequently associated with venous thromboembolisms, the presentation of multiple myeloma with pulmonary embolism as its initial manifestation is extremely rare. We report the case of a 60 y/o Hispanic male who presented with a Pulmonary Embolism, further diagnostic test revealed an underlying diagnosis of Multiple Myeloma.

American Journal of Medical Case Reports. 2015, 3(8), 244-246. DOI: 10.12691/ajmcr-3-8-6
Pub. Date: July 09, 2015

Full-Text PDF

14436 Views4129 Downloads

Primary Peritoneal Carcinoma: A Case Report of Primary Peritoneal Papilary Serous Adenocarcinoma in a 59 Year Old Postmenopausal Woman

by Solomon Gumanga, Edwin Mwintiereh Ta-ang Yenli and Saeed Jibreel

Case Report

Primary peritoneal carcinoma is rare and may present with symptoms similar to epithelial ovarian carcinoma which has some histological similarities. This is a case report of a 59 year old woman Para 2 who presented with massive ascites, abdominal pain, difficulty in breathing, abdominal mass and weight loss of three months duration. No conclusive diagnosis could be made after an ultrasound scan and CT-scan investigations showed the ovaries were of normal size but serum CA125 level was markedly elevated. No organ including the ovaries was identified as primary source of the tumour at an initial laparatomy. Specimens were however taken from multiple areas including the peritoneum and the omentum for histopathology. Reports of cytology and histology specimens indicated papillary serous adenocarcinoma with likely primary source being the ovary. Two cycles of neo-adjuvant chemotherapy was administered followed by re-laparatomy where total abdominal hysterectomy plus bilateral salpingoophorectomy, omectomy and surgical reduction of tumour seedlings. Final histopathology ruled out papillary serous adenocarcinoma of the ovary which has similar histological features with papillary serous adenocarcinoma of the peritoneum. Four cycles of adjuvant platinum plus paclitaxel based chemotherapy was then administered and serum CA 125 declined from 214u/ml to 49.5u/ml with no clinical signs of residual disease on completion of chemotherapy. The patient is now on followed-up. Conclusion: Primary peritoneal carcinoma though rare, should be suspected if the peritoneum is involved in a malignancy of an unknown primary source. Management of primary peritoneal carcinoma should involve surgical debulking and appropriate chemotherapy as in ovarian carcinoma.

American Journal of Medical Case Reports. 2015, 3(8), 239-243. DOI: 10.12691/ajmcr-3-8-5
Pub. Date: July 08, 2015

Full-Text PDF

13302 Views3654 Downloads4 Likes

Central Mucoepidermoid Carcinoma of Mandible: A Case Report

by Nafise Shamloo, Nasim Taghavi, Majid Nemati and Yaser Safi

Case Report

Central mucoepidermoid carcinoma (CMC) is an uncommon tumor, comprising 2-3 % of all mucoepidermoid carcinomas reported. The majority of cases occurring in the 4th and 5th decades of life and they are histologically low-grade malignant neoplasm usually affecting the mandible. The case presented is a 41 year old woman with central mucoepidermoid carcinoma at the left posterior of the mandible as a swelling with purulent discharge since last year. Radiographic examination showed a radiolucent lesion with well-defined borders in distal area of ┌8.

American Journal of Medical Case Reports. 2015, 3(8), 235-238. DOI: 10.12691/ajmcr-3-8-4
Pub. Date: July 06, 2015

Full-Text PDF

12362 Views2981 Downloads3 Likes

Transitional Cell Papilloma of Nasal Cavity with Malignant Transformation

by Vijaya KJ, Kaur P, Khurana A, Chauhan A, Singh G and Parmar P

Case Report

Inverted papilloma of nasal cavity is a rare tumor which is most commonly seen in 5^th to 7^th decade. A case is described here occurring in a 55 year old male who presented with left nasal cavity obstruction and bleeding from the left nose. The patient underwent incisional biopsy from growth nasal cavity which was suggesting transitional cell papilloma with suggestion of malignant transformation following by which the patient underwent left side lateral rhinotomy. Microscopic findings established the diagnosis of transitional cell carcinoma. Patient was later treated by external beam radiation therapy of dose 60 Gy in 30 fractions to the local site. Twenty months after treatment completion patient is on regular follow up and disease free on clinical and radiological examination.

American Journal of Medical Case Reports. 2015, 3(8), 231-234. DOI: 10.12691/ajmcr-3-8-3
Pub. Date: July 03, 2015

Full-Text PDF

16653 Views4359 Downloads1 Likes

Cerebral Gas Embolism - A Serious Complication of CO₂ Angiography

by SUMIT KAPOOR, Nariman Nezami, Ross Mazo and Jyotsana Thakkar

Case Report

Carbon dioxide angiography is routinely used for vascular imaging and endovascular procedures. It is very useful in patients with allergy to iodinated contrast agents or with poor renal function. It is relatively safe to use. We describe first case of cerebral gas embolism leading to multiple bilateral ischemic strokes in a patient receiving carbon dioxide angiography for workup of thrombosed arm arteriovenous fistula.

American Journal of Medical Case Reports. 2015, 3(8), 227-230. DOI: 10.12691/ajmcr-3-8-2
Pub. Date: July 02, 2015

Full-Text PDF

12413 Views3184 Downloads3 Likes

Left Paraduodenal Hernia: An Unusual Cause of Acute Intestinal Obstruction

by Thiam O, Toure AO, Gueye ML, Seck M, Cisse M, Foba ML, Ka O, Dieng M, Dia A and Toure CT

Case Report

Internal hernia is an unusual pathology. They are underestimated becauseit is usually asymptomatic. The diagnosis is usually done during a complication like the acute intestinal obstruction. We report a case of left paraduodenal internal hernia. He was received at the emergency in a clinical presentation of acute intestinal obstruction. The abdomino- pelvicCT scan could not confirm the diagnosis in preoperative. The laparotomy confirms the diagnosis. The treatment consisted in the reduction of intestines and the closing of the bag. The post-operative was simple after a year of follow-up.

American Journal of Medical Case Reports. 2015, 3(8), 225-226. DOI: 10.12691/ajmcr-3-8-1
Pub. Date: July 02, 2015

Full-Text PDF

12686 Views2912 Downloads4 Likes