Primary Splenic Diffuse Large B Cell Lymphoma after Splenectomy: A Rare Case with Literatur Review

Semra Ayturk¹, Mehmet Celik^1, , Onur Mert², Nuray Can³, Atakan Sezer⁴, Sibel Guldiken¹ and Ahmet Muzaffer Demir⁵

¹Department of Internal Medicine, Division of Endocrinology and Metabolism, Trakya Medical School, University of Trakya, Edirne, Turkey

²Department of Internal Medicine, Trakya Medical School, University of Trakya, Edirne, Turkey

³Department of Pathology, Trakya Medical School, University of Trakya, Edirne, Turkey

⁴Department of General Surgery, Trakya Medical School, University of Trakya, Edirne, Turkey

⁵Department of Internal Medicine, Division of Hematology, Trakya Medical School, University of Trakya, Edirne, Turkey

Cite this paper

Semra Ayturk, Mehmet Celik, Onur Mert, Nuray Can, Atakan Sezer, Sibel Guldiken and Ahmet Muzaffer Demir. Primary Splenic Diffuse Large B Cell Lymphoma after Splenectomy: A Rare Case with Literatur Review. American Journal of Medical Case Reports. 2015; 3(8):265-268. doi: 10.12691/AJMCR-3-8-11

Abstract

Primary splenic diffuse large B cell lymphoma is rarely clinical entity and comprises 1% of all malignant lymphomas. The spleen is also involved in immune defense against blood-borne antigens. Though the haematological malignancies, spleen is usually affected as a part of multisystemic involvement rather than isolated involvement. More than half of patients affected by Hodgkin's disease and about a third of those with non-Hodgkin lymphoma have splenic involvement. The involved spleen may be complicated with rupture due to massive splenomegaly, which may need urgent intervention. In this report, we present a 47-year-old female patient with massive splenomegaly, who was diagnosed with primary splenic diffuse large B cell lymphoma after splenectomy.

Keywords

diffuse large B-cell lymphoma, splenomegaly, splenic neoplasms

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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