Skip Navigation Links.
Collapse <span class="m110 colortj mt20 fontw700">Volume 12 (2024)</span>Volume 12 (2024)
Collapse <span class="m110 colortj mt20 fontw700">Volume 11 (2023)</span>Volume 11 (2023)
Collapse <span class="m110 colortj mt20 fontw700">Volume 10 (2022)</span>Volume 10 (2022)
Collapse <span class="m110 colortj mt20 fontw700">Volume 9 (2021)</span>Volume 9 (2021)
Collapse <span class="m110 colortj mt20 fontw700">Volume 8 (2020)</span>Volume 8 (2020)
Collapse <span class="m110 colortj mt20 fontw700">Volume 7 (2019)</span>Volume 7 (2019)
Collapse <span class="m110 colortj mt20 fontw700">Volume 6 (2018)</span>Volume 6 (2018)
Collapse <span class="m110 colortj mt20 fontw700">Volume 5 (2017)</span>Volume 5 (2017)
Collapse <span class="m110 colortj mt20 fontw700">Volume 4 (2016)</span>Volume 4 (2016)
Collapse <span class="m110 colortj mt20 fontw700">Volume 3 (2015)</span>Volume 3 (2015)
Collapse <span class="m110 colortj mt20 fontw700">Volume 2 (2014)</span>Volume 2 (2014)
Collapse <span class="m110 colortj mt20 fontw700">Volume 1 (2013)</span>Volume 1 (2013)
American Journal of Medical Case Reports. 2023, 11(3), 63-66
DOI: 10.12691/AJMCR-11-3-6
Case Report

Discovery of a Poly-metastatic Pulmonary Adenocarcinoma Following the Diagnosis of a Bone Lesion in the Mandible: A Case Report

Nabil Benahmed1, , Ryma Kabir2, Katarina Kontaxis3, Alice Becker4 and Nimaat Pertick5

1Resident Stomatology, Oral and Maxillofacial Surgery, University of Montreal Hospital Center (CHUM) – Canada

2Periodontology Departement, Professor, University of Montreal – Canada

3Oral and Maxillofacial Surgery Departement, Professor, University of Montreal – Canada

4Oral Surgery Department, Head of Clinic, University Hospital Assistant, Nancy Hospital Center (CHRU Nancy) – France

5Oral and Maxillofacial Surgery Department, Chief of Surgery, University of Montreal Hospital Center (CHUM) – Canada

Pub. Date: March 24, 2023

Cite this paper

Nabil Benahmed, Ryma Kabir, Katarina Kontaxis, Alice Becker and Nimaat Pertick. Discovery of a Poly-metastatic Pulmonary Adenocarcinoma Following the Diagnosis of a Bone Lesion in the Mandible: A Case Report. American Journal of Medical Case Reports. 2023; 11(3):63-66. doi: 10.12691/AJMCR-11-3-6

Abstract

Introduction: Metastases of the oral cavity are rare and concern only a tiny part of the neoplasias of the oral cavity. The detection of an atypical lesion should always alert the clinician to the possibility of primary or secondary cancerous involvement. Observation: The case presented here describes a patient presenting to the consultation for pain in the temporomandibular joint. A panoramic X-ray revealed an atypical osteolytic lesion located at the level of the left articular condyle. Additional investigations confirmed the existence of a lytic lesion indicating a metastasis or a primary sarcomatosis type. Complementary examinations made it possible to establish the diagnosis of a poly-metastatic pulmonary adenocarcinoma and to begin the management of the patient who was unaware of her condition. Conclusion: The discovery of an atypical bone lesion should alert the clinician and requires the performance of additional examinations to establish a diagnosis that can condition the survival of a patient.

Keywords

metastasis, mandibular condyle, pulmonary adenocarcinoma

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]  Hirshberg A, Berger R, Allon I, et al.. Metastatic tumors to the jaws and mouth. Head Neck Pathol 2014; 8: 463-74.
 
[2]  Pereira-Filho VA, Chaves MD, Haddad J, et al. Mandible metastasis as the first sign from primary adenocarcinoma of the lung. Gen Dent 2007; 55: 224-7.
 
[3]  Hirshberg A, Shnaiderman-Shapiro A, Kaplan I, Berger R. Metastatic tumors to the oral cavity - pathogenesis and analysis of 673 cases. Oral Oncol. 2008; 44: 743-752.
 
[4]  Matsuda S, Yoshimura H, Yoshida H, et al.. Mandibular metastasis as the first clinical indication of occult lung adenocarcinoma with multiple metastases: a case report. Medicine 2018; 97: e0296.
 
[5]  Bodner L, Sion-Vardy N, Geffen DB, et al.. Metastatic tumors to the jaws: a report of eight new cases. Med Oral Patol Oral Cir Bucal 2006; 11: E132-5.
 
[6]  Scrivani SJ, Keith DA, Kaban LB. Troubles temporo-mandibulaires. N Engl J Méd. 2008; 359(25): 2693-2705.
 
[7]  Kaur H, Mishra D, Manchanda S, Bhutia O. Mandibular tumour as the primary manifestation of an occult adenocarcinoma. BMJ Case Rep. 2021 Jan 7; 14(1): e239151.
 
[8]  Kruse AL, Luebbers HT, Obwegeser JA, Edelmann L, Graetz KW. Temporomandibular disorders associated with metastases to the temporomandibular joint: a review of the literature and 3 additional cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010 Aug; 110(2): e21-8.
 
[9]  Valesan LF, Da-Cas CD, Réus JC, Denardin ACS, Garanhani RR, Bonotto D, Januzzi E, de Souza BDM. Prevalence of temporomandibular joint disorders: a systematic review and meta-analysis. Clin Oral Investig. 2021 Feb; 25(2): 441-453.
 
[10]  Lee DS, Kang JH, Lee CG, et al. Predicting survival in patients with advanced non-squamous non-small cell lung cancer: validating the extent of metastasis. Cancer Res Treat 2013; 45: 95-102.
 
[11]  Popper HH. Progression and metastasis of lung cancer. Cancer Metastasis Rev 2016; 35: 75-91.