Skip Navigation Links.
Collapse <span class="m110 colortj mt20 fontw700">Volume 12 (2024)</span>Volume 12 (2024)
Collapse <span class="m110 colortj mt20 fontw700">Volume 11 (2023)</span>Volume 11 (2023)
Collapse <span class="m110 colortj mt20 fontw700">Volume 10 (2022)</span>Volume 10 (2022)
Collapse <span class="m110 colortj mt20 fontw700">Volume 9 (2021)</span>Volume 9 (2021)
Collapse <span class="m110 colortj mt20 fontw700">Volume 8 (2020)</span>Volume 8 (2020)
Collapse <span class="m110 colortj mt20 fontw700">Volume 7 (2019)</span>Volume 7 (2019)
Collapse <span class="m110 colortj mt20 fontw700">Volume 6 (2018)</span>Volume 6 (2018)
Collapse <span class="m110 colortj mt20 fontw700">Volume 5 (2017)</span>Volume 5 (2017)
Collapse <span class="m110 colortj mt20 fontw700">Volume 4 (2016)</span>Volume 4 (2016)
Collapse <span class="m110 colortj mt20 fontw700">Volume 3 (2015)</span>Volume 3 (2015)
Collapse <span class="m110 colortj mt20 fontw700">Volume 2 (2014)</span>Volume 2 (2014)
Collapse <span class="m110 colortj mt20 fontw700">Volume 1 (2013)</span>Volume 1 (2013)
American Journal of Medical Case Reports. 2024, 12(2), 21-23
DOI: 10.12691/AJMCR-12-2-3
Case Report

Focal Takotsubo Cardiomyopathy: A Case Report and Literature Review

Jesus Romero1, , Rachel Abboud Yezin Shamoon2, 2, Sherif Elkattawy2, Rahul Vasudev2 and Fayez Shamoon2

1Internal Medicine Department, RWJBarnabas Health/Trinitas Regional Medical Center, Elizabeth, New Jersey, USA

2Cardiology Department, St. Joseph’s University Medical Center, Paterson, New Jersey, USA

Pub. Date: February 27, 2024

Cite this paper

Jesus Romero, Rachel Abboud Yezin Shamoon, Sherif Elkattawy, Rahul Vasudev and Fayez Shamoon. Focal Takotsubo Cardiomyopathy: A Case Report and Literature Review. American Journal of Medical Case Reports. 2024; 12(2):21-23. doi: 10.12691/AJMCR-12-2-3

Abstract

Takotsubo cardiomyopathy (TCC) or stress-induced cardiomyopathy, was first discovered in Japan in 1990 and is derived from the name “octopus pod” which describes the typical LV apical ballooning with a narrow base. The pathophysiology behind takotsubo remains incompletely understood. However, TCC association with conditions of catecholamine excess such as emotional or physical stress is well studied and is the most favored theory thus far. Atypical, rare forms of TCC such as mid-ventricular, basal, focal, and apical types have been identified with an incidence of 14.6%, 2.2%, 1.5%, and 81.7% respectively. We present the case of a 48-year-old Caucasian female admitted status post seizure and drowning incident who was hemodynamically stable and with a physical examination grossly unremarkable on presentation. Her echocardiogram showed hypokinesis and regional wall motion abnormality involving the anterior septal and lateral walls. Her cardiac magnetic resonance imaging showed hypokinesia of the anterolateral mid to basal wall consistent with focal Takobsubo cardiomyopathy. The patient underwent cardiac catheterization, which showed non-obstructive coronary artery disease with anterolateral dyskinesis. She was discharged with close follow-up as an outpatient.

Keywords

focal takotsubo cardiomyopathy, atypical takotsubo cardiomyopathy, cardiac resonance imaging

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]  Templin C, Ghadri JR, Diekmann J, et al. Clinical Features and Outcomes of Takotsubo (Stress) Cardiomyopathy. New England Journal of Medicine. 2015.
 
[2]  Vasudev R, Rampal U, Patel H, Patel K, Bikkina M, Shamoon F. Selective Serotonin–norepinephrine Reuptake Inhibitors-induced Takotsubo Cardiomyopathy. North American Journal of Medical Sciences. 2016.
 
[3]  Boyd B, and Solh T. Takotsubo cardiomyopathy: Review of broken heart syndrome. Journal of the American Academy of PAs. 2020.
 
[4]  Patel MR, Singh M, Gersh BJ, O’Neill W. ST-SEGMENT ELEVATION MYOCARDIAL INFARCTION. Hurst's The Heart. 14e New York, NY: McGraw-Hill. 2018.
 
[5]  Kato K, Kitahara H, Fujimoto Y, et al. Prevalence and Clinical Features of Focal Takotsubo Cardiomyopathy. Circ J. 2016.
 
[6]  Zbinden R, Mutter M, Weishaupt D. Case Report Cardiac Magnetic Resonance Imaging in the Diagnosis of Anterolateral Left Ventricular Ballooning, a Variant of Classic Takotsubo Cardiomyopathy. Case Reports in Cardiology. 2012.
 
[7]  Cheshire C, Nerlekar N, Nasis A, Moir S. Focal Takotsubo Cardiomyopathy- Insights from Cardiac MRI Imaging. Heart Lung Circ. 2017.
 
[8]  Ghadri JR, Cammann VL, Napp LC, et al. Differences in the clinical profile and outcomes of typical and atypical takotsubo syndrome: Data from the international takotsubo registry. JAMA Cardiol. 2016.
 
[9]  Damodaran S, Mrozek E, Liebner D, Kendra K. Focal takotsubo cardiomyopathy with high-dose interleukin-2 therapy for malignant melanoma. JNCCN J Natl Compr Cancer Netw. 2014.
 
[10]  Suzuki K, Osada N, Akasi YJ, et al. An atypical case of “Takotsubo cardiomyopathy” during alcohol withdrawal: abnormality in the transient left ventricular wall motion and a remarkable elevation in the ST segment. Intern Med. 2004.
 
[11]  Kato K, Sakai Y, Ishibashi I, Kobayashi Y. Transient focal left ventricular ballooning: A new variant of Takotsubo cardiomyopathy. Eur Heart J Cardiovasc Imaging. 2015.
 
[12]  Villareal R, Achari A, Wilansky S, and Wilson JM. Anteroapical Stunning and Left Ventricular Outflow Tract Obstruction. Mayo Clin Proc. 2001.
 
[13]  Sharkey S, Lesser JR, Zenovich AG, et al. Acute and Reversible Cardiomyopathy Provoked by Stress in Women From the United States. Circulation. 2005.
 
[14]  Bybee KA, Kara T, Prasad A, et al. Systematic Review: Transient Left Ventricular Apical Ballooning: A Syndrome That Mimics ST-Segment Elevation Myocardial Infarction. Ann Intern Med. 2004.