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American Journal of Medical Case Reports. 2024, 12(2), 24-28
DOI: 10.12691/AJMCR-12-2-4
Case Report

Oral Pemphigus Vulgaris: A Case Report and Literature Review

Abdulhameed Alsarraf1, 2, , Shaima Aldhafeeri1 and Woroud N. AL-Sulimmani3

1Oral Medicine Clinic, Ministry of Health, Jahra Medical City, Kuwait

2Oral Medicine & Pathology Clinic, Kuwait Oil Company Hospital, Al-Ahmadi, Kuwait

3Oral & Maxillofacial Surgery Department, Ministry of Health, Kuwait

Pub. Date: March 02, 2024
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Cite this paper

Abdulhameed Alsarraf, Shaima Aldhafeeri and Woroud N. AL-Sulimmani. Oral Pemphigus Vulgaris: A Case Report and Literature Review. American Journal of Medical Case Reports. 2024; 12(2):24-28. doi: 10.12691/AJMCR-12-2-4

Abstract

Pemphigus vulgaris (PV) is a rare chronic autoimmune mucocutaneous blistering disease characterized by the production of autoantibodies targeting desmogleins, key components of intercellular adhesion of keratinocytes. This process leads to the loss of intercellular adhesion, culminating in the development of intraepithelial bullae and erosions. PV manifest as intraoral lesions that subsequently spread to other mucous membranes and the skin. While the exact etiology remains elusive, several triggering factors have been identified. Oral lesions of PV are often misdiagnosed and mistreated, emphasizing the need for early recognition by dental professionals. This case report aims to contribute to the existing literature by illustrating representative clinical features of PV, diagnostic approach, and therapeutic challenges associated with our case.

Keywords

pemphigus vulgaris, oral ulceration, autoantibodies, autoimmune

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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