Jejunal Gastrointestinal Stromal Tumor Associated with Synchronous Periampullary Adenocarcinoma – A Case Report

Kumar Jayant^1, , Swati Agrawal² and Rajendra Agarwal³

¹Department of Surgery, Sudha Hospital & Medical Research Centre Kota, Rajasthan, India

²Sudha Hospital & Medical Research Centre, Talwandi, Kota, Rajasthan, India

³Director & Head of Department of Surgery, Sudha Hospital & Medical Research Centre Kota, Rajasthan, India

Cite this paper

Kumar Jayant, Swati Agrawal and Rajendra Agarwal. Jejunal Gastrointestinal Stromal Tumor Associated with Synchronous Periampullary Adenocarcinoma – A Case Report. American Journal of Medical Case Reports. 2014; 2(1):12-15. doi: 10.12691/AJMCR-2-1-4

Abstract

Gastrointestinal stromal tumors (GIST) are rare mesenchymal neoplasms of the gastrointestinal tract with a malignant potential and unpredictable behavior. In the literature very few cases of synchronous development of a GIST with other neoplasia of different incidence, etiology, evolution and prognosis have been described.

Keywords

gastrointestinal stromal tumors, pancreatic adenocarcinoma, synchronous tumors

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]	Theodosopoulos T, Dellaportas D, Psychogiou V, et al. Synchronous gastric adenocarcinoma and gastrointestinal stromal tumor (GIST) of the stomach: a case report. World J Surg Oncol 2011; 9: 60.
[2]	Corless CL, Fletcher JA, Heinrich MC. Biology of gastrointestinal stromal tumors. J Clin Oncol 2004; 22: 3813-3825.
[3]	Miettinen M, Lasota J. Gastrointestinal stromal tumors-definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis. Virchows Arch 2001; 438: 1-12.
[4]	Neves LR, Oshima CT, Artigiani-Neto R, Yanaguibashi G, Lourenço LG, Forones NM.. Ki67 and p 53 in gastrointestinal stromal tumors–GIST. Arq Gastroenterol 2009; 46: 116-120.
[5]	Maiorana A, Fante R, Maria Cesinaro A, Adriana Fano R. Synchronous occurrence of epithelial and stromal tumors in the stomach: a report of 6 cases. Arch Pathol Lab Med 2000; 124: 682-686.
[6]	Wronski M, Ziarkiewicz-Wroblewska B, Gornicka B, et al. Synchronous occurrence of gastrointestinal stromal tumors and other primary gastrointestinal neoplasms. World J Gastroenterol 2006; 12: 5360-5362.
[7]	Kang YN, Jung HR, Hwang I. Clinicopathological and immunohistochemical features of gastrointestinal stromal tumors. Cancer Res Treat 2010; 42: 135-143.
[8]	Yamamoto D, Hamada Y, Tsubota Y, Kawakami K, Yamamoto C, Yamamoto M. Simultaneous development of adenocarcinoma and gastrointestinal stromal tumor (GIST) in the stomach: Case report. World J Surg Oncol 2012; 10: 6.
[9]	Pandurengan RK, Dumont AG, Araujo DM, et al. Survival of patients with multiple primary malignancies: a study of 783 patients with gastrointestinal stromal tumor. Ann Oncol 2010; 21: 2107-2111.
[10]	Sugimura T, Fujimura S, Baba T. Tumor production in the glandular stomach and alimentary tract of the rat by N-methyl-N’-nitro-N-nitrosoguanidine. Cancer Res 1970; 30: 455-465.
[11]	Liu YJ, Yang Z, Hao LS, Xia L, Jia QB, Wu XT. Synchronous incidental gastrointestinal stromal and epithelial malignant tumors. World J Gastroenterol 2009; 15: 2027-2031.