Skip Navigation Links.
Collapse <span class="m110 colortj mt20 fontw700">Volume 12 (2024)</span>Volume 12 (2024)
Collapse <span class="m110 colortj mt20 fontw700">Volume 11 (2023)</span>Volume 11 (2023)
Collapse <span class="m110 colortj mt20 fontw700">Volume 10 (2022)</span>Volume 10 (2022)
Collapse <span class="m110 colortj mt20 fontw700">Volume 9 (2021)</span>Volume 9 (2021)
Collapse <span class="m110 colortj mt20 fontw700">Volume 8 (2020)</span>Volume 8 (2020)
Collapse <span class="m110 colortj mt20 fontw700">Volume 7 (2019)</span>Volume 7 (2019)
Collapse <span class="m110 colortj mt20 fontw700">Volume 6 (2018)</span>Volume 6 (2018)
Collapse <span class="m110 colortj mt20 fontw700">Volume 5 (2017)</span>Volume 5 (2017)
Collapse <span class="m110 colortj mt20 fontw700">Volume 4 (2016)</span>Volume 4 (2016)
Collapse <span class="m110 colortj mt20 fontw700">Volume 3 (2015)</span>Volume 3 (2015)
Collapse <span class="m110 colortj mt20 fontw700">Volume 2 (2014)</span>Volume 2 (2014)
Collapse <span class="m110 colortj mt20 fontw700">Volume 1 (2013)</span>Volume 1 (2013)
American Journal of Medical Case Reports. 2014, 2(1), 19-21
DOI: 10.12691/AJMCR-2-1-6
Case Report

A Rare Case of Chronic Myeloid Leukemia At a Patient with Achondroplasia

Ilknur Nizam1, , Mehmet Ali Erkurt1, Ilhami Berber1, Emin Kaya1 and Irfan Kuku1

1Department of Hematology, Faculty of Medicine, Inonu University, Malatya, Turkey

Pub. Date: January 17, 2014

Cite this paper

Ilknur Nizam, Mehmet Ali Erkurt, Ilhami Berber, Emin Kaya and Irfan Kuku. A Rare Case of Chronic Myeloid Leukemia At a Patient with Achondroplasia. American Journal of Medical Case Reports. 2014; 2(1):19-21. doi: 10.12691/AJMCR-2-1-6

Abstract

The coincidence of chronic myeloid leukemia (CML) and achondroplastic dwarfism is very rare. A 40-year old man with achondroplastic dwarfism was diagnosed with chronic myeloid leukemia in blastic phase with a Sokal index of 1.34. Standart dose imatinib treatment was immediately started after the diagnosis.

Keywords

chronic myeloid leukemia, achondroplasia, CML, achondroplastic dwarfism

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]  Geromin A, Sperotto A, Fanin R, Damiani D, Michieli M, Baccarani M. Bone marrow transplantation in a patient with chronic myeloid leukemia and achondroplasia. Haematologica. 1997 Nov-Dec; 82 (6): 703-4.
 
[2]  Karkuzhali P, Shanthi V, Usha. T A case of chronic myeloid leukaemia presenting as megakaryocytic blast crisis (AML M7) Ecancermedicalscience. 2013; 7: 375.
 
[3]  Van Etten RA. c-Abl regulation: a tail of two lipids. Curr Biol 2003; 13: R608.
 
[4]  Jabbour E, Kantarjian H: Chronic myeloid leukemia: 2012 update on diagnosis, monitoring, and management. Am J Hematol 87 (11): 1037-45, 2012.
 
[5]  Stoll C, Feingold J. Do Parents and Grandparents of Patients With Achondroplasia Have a Higher Cancer Risk? American Journal of Medical Genetics 130A: 165-168 (2004).
 
[6]  Kantarjian HM, Hochhaus A, Saglio G, et al.: Nilotinib versus imatinib for the treatment of patients with newly diagnosed chronic phase, Philadelphia chromosome-positive, chronic myeloid leukaemia: 24-month minimum follow-up of the phase 3 randomised ENESTnd trial. Lancet Oncol 12 (9): 841-51, 2011.