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American Journal of Medical Case Reports. 2014, 2(10), 225-226
DOI: 10.12691/AJMCR-2-10-7
Case Report

Simultaneous Presentation of Metastatic Cancer and Primary Hyperparathyroidism – A Case Series

Hiang Leng Tan1, , Muhammad Imran Butt2 and Najeeb Waheed3

1Department of Diabetes and Endocrinology, Weston General Hospital, Weston-super-Mare, UK

2Department of Diabetes and Endocrinology, Peterborough City Hospital, Peterborough, UK

3Department of Diabetes and Endocrinology, Hereford County Hospital, Hereford, UK

Pub. Date: October 23, 2014
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Cite this paper

Hiang Leng Tan, Muhammad Imran Butt and Najeeb Waheed. Simultaneous Presentation of Metastatic Cancer and Primary Hyperparathyroidism – A Case Series. American Journal of Medical Case Reports. 2014; 2(10):225-226. doi: 10.12691/AJMCR-2-10-7

Abstract

The objective of our two case reports is to increase awareness of the simultaneous occurrence of primary hyperparathyroidism and malignancy in patients that presents with hypercalcaemia. This report reviews the case reports from the history, investigation, treatment and outcome for these two patients. A literature review of the association between malignancy and primary hyperparathyroidism was also performed. Both patients had metastatic cancer and primary hyperparathyroidism but died within months of diagnosis despite treatment for their primary malignancy. This serves as a reminder that these two separate diagnoses do exist, though it did not alter the outcome of our patients. However, we propose that in patients with malignancy who presents with hypercalcaemia and non-suppressed PTH level, further workup should be instigated to rule out primary hyperparathyroidism as surgical option is potentially curative for the latter.

Keywords

primary hyperparathyroidism, metastatic cancer, hypercalcaemia

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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