Sheehan’s Syndrome: A Case Report

Mohammed Nasir Uddin^1, , Mohammed Abbas Uddin Chy² and Taslima Khan³

¹Assistant Professor, Department of Medicine, BGC Trust Medical College

²Associate Professor, Department of Radiology & Imaging, BGC Trust Medical College

³Clinical Sonologist & General Physician

Cite this paper

Mohammed Nasir Uddin, Mohammed Abbas Uddin Chy and Taslima Khan. Sheehan’s Syndrome: A Case Report. American Journal of Medical Case Reports. 2014; 2(3):50-51. doi: 10.12691/AJMCR-2-3-2

Abstract

Sheehan’s syndrome is defined by varying degrees of anterior pituitary deficiency due to postpartumischemic necrosis of the pituitary gland after massive bleeding. Sheehan’s syndrome, though rare, is still one of the commonest causes of hypopituitarism in developing countries like ours. The clinical presentation is variable with abrupt or insidiously developing pituitary insufficiency after a heavy intra-partum or postpartum haemorrhage. We present an young lady with this syndrome who had slowly progressive panhypopituitarism 6 years after a severe haemorrhage associated with the delivery of a male baby.

Keywords

Sheehan's syndrome, hypopituitarism, post partum ischaemic necrosis

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]	Sheehan HL. Simmonds disease due to postpartum necrosis of the anterior pituitary following postpartum haemorrhage. Q JMed 1939; 32: 277-309.
[2]	Kelestimur F. Sheehan’s syndrome. Pitutary 2003; 6:181-188
[3]	Huang YY, Ting MK, Hsu BR, Tsai JS: Demonstration of reserved anteriorpituitary function among patients with amenorrhea after postpartumhemorrhage. GynecolEndocrinol 2000, 14(2):99-104.
[4]	Gokalp D, Tuzcu A, Bahceci M, Arikan S, Bahceci S, Pasa S: Sheehan’ssyndrome as a rare cause of anemia secondary to hypopituitarism. AnnHematol 2009, 88(5):405-410.
[5]	Kim DY, Kim JH, Park YJ, Jung KH, Chung HS, Shin S, Yun SS, Park S, Kim BK:Case of complete recovery of pancytopenia after treatment ofhypopituitarism. Ann Hematol 2004, 83(5): 309-312.
[6]	Laway BA, Bhat JR, Mir SA, Khan RS, Lone MI, Zargar AH: Sheehan’ssyndrome with pancytopenia–complete recovery after hormonereplacement (case series with review). Ann Hematol 2010, 89(3): 305-308.
[7]	Perraudin V, Lefebvre H, Kuhn JM. Insuffisanceantéhypophysaire. EncyclMéd chi (Paris), Endocrinologie-Nutrition 10 - 019 – A-10, 1-12, 1992
[8]	Assan R. Urgencesmétaboliques et endocriniennes In: KleinknechtD,éd. Principes de réanimationmédicales, 3e éd.Paris : Flammarion médecine sciences, 1984 :292-326
[9]	Merger R, Levy J, Melchior J. Précis d’obstétrique, 4e édition. Paris : Masson, 1974 : 321-31.
[10]	Molitch ME. Pituitary diseases in pregnancy. SeminPerinatol1998 ; 22 : 457-70.
[11]	Jialal I, Naidoo C ,Norman RJ, Rajput MC, Omar MA, Joubert SM. Pituitary function in sheehan’s syndrome. ObstetGynecol 1984; 63: 15-9.
[12]	Olivennes F, Harmas A, Frydman R. L’induction de l’ovulation : strategies thérapeutiquesRéalités en Gynécologie- Obstétrique 1998; 28: 19-21.