American Journal of Medical Case Reports. 2014, 2(6), 117-119
DOI: 10.12691/AJMCR-2-6-2
Diarrhea, Demyelinating Neuropathy and Dyspnea: An Occam’s Razor Dilemma
Abimbola Aderinto-Adike1, , Hung Q Doan1, Cima Nowbakht1, Elizabeth Looke-Stewart1 and Soma Jyothula2
1Houston Methodist Hospital, Department of Medicine, 6565 Fannin Street, Houston TX 77030 USA
2Houston Methodist Hospital, Department of Pulmonary and Transplant Medicine, 6565 Fannin Street, Houston TX 77030 USA
Pub. Date: June 24, 2014
Cite this paper
Abimbola Aderinto-Adike, Hung Q Doan, Cima Nowbakht, Elizabeth Looke-Stewart and Soma Jyothula. Diarrhea, Demyelinating Neuropathy and Dyspnea: An Occam’s Razor Dilemma.
American Journal of Medical Case Reports. 2014; 2(6):117-119. doi: 10.12691/AJMCR-2-6-2
Abstract
POEMS disease is a rare paraneoplastic syndrome resulting from an underlying plasma cell disorder. We present a unique case of POEMS disease with predominant clinical symptoms of diarrhea and paresthesias.
Keywords
POEMS disease, paraneoplastic disease, diarrhea, paresthesias, shortness of breath
Copyright
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References
[1] | Nakanishi T, Sobue I, Toyokura Y, Nishitani H, Kuroiwa Y, Satoyoshi E, Tsubaki T, Igata A, Ozaki Y. The Crow-Fukase syndrome: a study of 102 cases in Japan. Neurology. 1984 Jun; 34 (6): 712-20. |
|
[2] | Bardwick P., Zvaifler N., Gill G., Newman D., Greenway, G., Resnick D. Plasma cell dyscrasia with polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes: the POEMS syndrome. Report on two cases and a review of the literature. Medicine (Baltimore). 1980 Jul; 59 (4): 311-322. |
|
[3] | Dispenzieri A, Buadi FK. A review of POEMS syndrome. Oncology (Williston Park). 2013 Dec; 27 (12): 1242-50. (1). |
|
[4] | Dispenzieri A. POEMS syndrome: 2014 update on diagnosis, risk-stratification, and management. Am J Hematol. 2014 Feb; 89 (2): 214-23. (2). |
|
[5] | Sekiguchi Y, Misawa S, Shibuya K, Nasu S, Mitsuma S, Iwai Y, Beppu M, Sawai S, Ito S, Hirano S, Nakaseko C, Kuwabara S. Ambiguous effects of anti-VEGF monoclonal antibody (bevacizumab) for POEMS syndrome. J Neurol Neurosurg Psychiatry. 2013 Dec; 84 (12): 1346-8. (3). |
|
[6] | Li J, Zhou DB. New advances in the diagnosis and treatment of POEMS syndrome. Br J Haematol. 2013 May; 161 (3): 303-15. (4). |
|
[7] | Dupont SA, Dispenzieri A, Mauermann ML, Rabinstein AA, Brown RD Jr. Cerebralinfarction in POEMS syndrome: incidence, risk factors, and imaging characteristics. Neurology. 2009 Oct 20; 73 (16): 1308-12. (5). |
|