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American Journal of Medical Case Reports. 2014, 2(8), 161-163
DOI: 10.12691/AJMCR-2-8-5
Case Report

Blastoid Variant of Mantle Cell Lymphoma- a Rare Case Report

Rajeev sen1, Sumiti Gupta1, Meenu Gill1, Rachneet Kohli1, Veena Gupta1 and Renuka Verma1,

1Department of Pathology, Pt. B.D. Sharma PGIMS Rohtak, Haryana

Pub. Date: August 31, 2014

Cite this paper

Rajeev sen, Sumiti Gupta, Meenu Gill, Rachneet Kohli, Veena Gupta and Renuka Verma. Blastoid Variant of Mantle Cell Lymphoma- a Rare Case Report. American Journal of Medical Case Reports. 2014; 2(8):161-163. doi: 10.12691/AJMCR-2-8-5

Abstract

Mantle cell lymphoma is now recognised as a rare but distinct entity in the revised WHO classification. It is now well recognised that MCL represent a broad spectrum of different histopathological subtypes. The term blastic or blastoid variant is generally used to describe cases with a homogeneous population of cells displaying lymphoblastic morphology. The blastic form of MCL may be difficult to diagnose however immunophenotyping and molecular analysis show typical mantle cell lymphoma pattern. We present a case of 30 year old male presenting with inguinal mass which was diagnosed as blastic transformation of mantle cell lymphoma based on routine histopathology and immunohistochemistry.

Keywords

mantle cell lymphoma, blastoid variant, immunohistochemistry

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]  Banks PM, Chan J, Cleary ML, Delsol G, De Wolf-Peeters G, Gatter K et al. Mantle cell lymphoma. A proposal for unification of morphologic, immunologic and molecular data. Am J Surg Pathol 1992; 16: 637-40.
 
[2]  Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H et al. WHO classification of tumours of haematopoietic and lymphoid tissues. Lyon: IARC, 2008.
 
[3]  Campos E, Raffeld M, Jaffe ES. Mantle-cell lymphoma. Semin Hematol 1999; 36: 115-27.
 
[4]  Morton LM, Wang SS, Devesa SS et al. Lymphoma incidence patterns by WHO subtype in the United States, 1992-2001. Blood 2006; 107: 265-76.
 
[5]  Barista I, Romaguera JE, Cabanillas F. Mantle-cell lymphoma. Lancet Oncol 2001; 3: 141-48.
 
[6]  Gao J, Peterson L, Nelson B, Goolsby C, Chen YH. Immunophenotypic variations in mantle cell lymphoma. Am J Clin Pathol. 2009; 132 (5): 699-706.
 
[7]  Bernard M, Gressin R, Lefrere F, et al. Blastic variant of mantle cell lymphoma: a rare but highly aggressive subtype. Leukemia 2001; 15: 1785-91.