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American Journal of Medical Case Reports. 2015, 3(10), 329-332
DOI: 10.12691/AJMCR-3-10-7
Case Report

Recurrent Nasal Sebaceous Carcinoma in Human Immunodefiency Virus/ Hepatitis B Virus (HIV/HBV) Coinfection Patient: A Case Report

Adel Alothman1 and Hythum Salah H. Mohamed1,

1Department of Medicine, Division of Infectious Diseases, King Abdulaziz Medical City, Riyadh, Sudan

Pub. Date: September 14, 2015

Cite this paper

Adel Alothman and Hythum Salah H. Mohamed. Recurrent Nasal Sebaceous Carcinoma in Human Immunodefiency Virus/ Hepatitis B Virus (HIV/HBV) Coinfection Patient: A Case Report. American Journal of Medical Case Reports. 2015; 3(10):329-332. doi: 10.12691/AJMCR-3-10-7

Abstract

Background: Human Immunodefiency Virus (HIV) since the first case was reported is recognized as a major risk factor for development of different types of malignancies, Sebaceous carcinoma is a rare and aggressive form of cutaneous carcinoma and very rare in HIV Patients. Method: A case report and literature review of 46 years old male, known to have HIV/HBV coinfection presented with a history of four months of gradual growth Nasal mass. Result: Excisional biopsy performed for the nasal mass and histopathology examination showed sebaceous cell carcinoma, Surgical removal of the nasal mass was done and nasal reconstruction with right paramedian forehead flap plus full thickness skin graft taken from the abdomen for reconstruction of the inner nose also was done, after two years patient came back with recurrent at same site. Conclusion: sebaceous cell carcinoma is an extremely rare in HIV patients, but should be considers for any skin tumor in HIV patient, follow up also needed for the risk of recurrent.

Keywords

nasal, sebaceous carcinoma, HIV, HBV

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]  Chopra KF, Tyring SK. The impact of the human immunodeficiency virus on the human papillomavirus epidemic. Arch Dermatol 1997;133:629-33.
 
[2]  Maurer TA, Christian KV, Kerschmann RL, et al. Cutaneous squamous cell carcinoma in human immunodeficiency virus-infected patients; a study of epidemiologic risk factors, human papillomavirus, and p53 expression. Arch Dermatol 1997;133:577-83.
 
[3]  Cappiello G, Garbuglia AR, Salvi R, et al. HIV infection increases the risk of squamous intra-epithelial lesions in women with HPV infection: an analysis of HPV genotypes Int J Cancer 1997;72:982-6.
 
[4]  Wang CY, Brodland DG, Su WP Skin cancers associated with acquired immunodeficiency syndrome. Mayo Clin Proc 1995; 70: 766772
 
[5]  Moloney FJComber HO’Lorcain PO’Kelly PConlon PJMurphy GM A population based study of skin cancer incidence and prevalence in renal transplant recipients. Br J Dermatol 2006; 154 (3) 498-504.
 
[6]  Maurer TAChristian KVKerschmann RL et al. Cutaneous squamous cell carcinoma in human immunodeficiency virus–infected patients: a study of epidemiologic risk factors, human papillomavirus, and p53 expression. Arch Dermatol 1997;133 (5) 577-583.
 
[7]  Lobo DVChu PGrekin RCBerger TG Nonmelanoma skin cancers and infection with the human immunodeficiency virus. Arch Dermatol 1992;128 (5) 623-627.
 
[8]  Saladi RNPersaud AN The causes of skin cancer: a comprehensive review. Drugs Today (Barc) 2005;41 (1) 37-53.
 
[9]  Mehrany KWeenig RHLee KKPittelkow MROtley CC Increased metastasis and mortality from cutaneous squamous cell carcinoma in patients with chronic lymphocytic leukemia. J Am AcadDermatol 2005;53 (6) 1067-1071.
 
[10]  Moloney FJComber HO’Lorcain PO’Kelly PConlon PJMurphy GM A population based study of skin cancer incidence and prevalence in renal transplant recipients. Br J Dermatol 2006;154 (3) 498-504.
 
[11]  Crum-Cianflone N, Hullsiek KH, Satter E, et al. Cutaneous malignancies among HIV-infected persons. Arch Intern Med. 2009;169(12):1130-1138.
 
[12]  Dasgupta T, Wilson LD, Yu JB. A retrospective review of 1349 cases of sebaceous carcinoma. Cancer. 2009 Jan 1;115(1):158-65.
 
[13]  Menezes CK, Gomes NM, Martins TG. Extra ocular sebaceous adenocarcinoma in HIV-positive patient - case report. An Bras Dermatol [serial on the Internet]. 2013 November [cited 2014 May 20].;88(6) Available from:http://www.ncbi.nlm.nih.gov/pubmed/24346870.
 
[14]  Engels EA. Non-AIDS defining malignancies in HIV-infected persons: etiologic puzzles, epidemiologic perils, prevention opportunities. AIDS. 2009;23:875-885.
 
[15]  Yen MT, Tse DT. Sebaceous Cell Carcinoma of the Eyelid and the Human Immunodeficiency Virus. Ophthal Plast Reconstr Surg. 2000;16:206-210.
 
[16]  Engels EA, Biggar RJ, Hall HI, et al. Cancer risk in people infected with human immunodeficiency virus in the United States. International Journal of Cancer 2008; 123(1):187-194.
 
[17]  Engels EA, Pfeiffer RM, Goedert JJ, et al. Trends in cancer risk among people with AIDS in the United States 1980-2002. AIDS 2006; 20(12):1645-1654.
 
[18]  Nelson BR, Hamlet KR, Gillard M, Railan D, Johnson TM. Sebaceous carcinoma. J Am Acad Dermatol 1995;33:1-15.
 
[19]  Afroz N, Zaidi N, Rizvi SA. Sebaceous carcinoma with apocrine differentiation: a rare entity with aggressive behavior. Indian J Pathol Microbiol [homepage on the Internet]. 2013 October [cited 2014 May 19].;56 4) Available from: http://http://www.ncbi.nlm.nih.gov/pubmed/24441233.