Atypical Myositis Presenting with Peripheral Neuropathy

Imene Boukhris^1, , Samira Azzabi¹, Ines kechaou¹, Eya Chérif¹, Anis Hariz¹, Chékib Kooli¹, Lamia Ben Hassine¹ and Narjes Khalfallah¹

¹Internal Medicine Department, University hospital of Charles Nicolle, Tunis, Tunisia

Cite this paper

Imene Boukhris, Samira Azzabi, Ines kechaou, Eya Chérif, Anis Hariz, Chékib Kooli, Lamia Ben Hassine and Narjes Khalfallah. Atypical Myositis Presenting with Peripheral Neuropathy. American Journal of Medical Case Reports. 2015; 3(12):419-421. doi: 10.12691/AJMCR-3-12-10

Abstract

Necrotizing Autoimmune Myositis (NAM) is an Acute autoimmune disease of the proximal skeletal muscle. The increased rate of morbidity and mortality in NAM is related to the severety and extant of muscle weakness. Patients with NAM develop antibodies to a specific signal recognition particle (anti-SRP ab). Peripheral neuropathy is extremely rare during the course of the disease. We report the case of a 35 y old male, hospitalized for severe proximal and distal muscle weakness with positive anti-SRB ab and concomitant peripheral neuropathy. The outcome was severe respiratory failure and death.

Keywords

necrotizing myopathy, anti-signal recognition particle (SRP) autoantibody, peripheral neuropathy

Copyright

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