Hypoglyceamia due to Paranoeplastic Secretion of Insulin in a Patient with Metastasizing Colon Cancer

Nadia Charfi¹, Lilia Affes¹, Mouna Elleuch^1, , Wafa Ben Saada¹, Nabila Rkik¹, Faten Hadj Kacem¹, Mouna Mnif¹, Fatma Mnif¹ and Mohamed Abid¹

¹Departement of Endocrinology, Diabetolgy, Hedi Chaker Hospital, Sfax, Tunisia

Cite this paper

Nadia Charfi, Lilia Affes, Mouna Elleuch, Wafa Ben Saada, Nabila Rkik, Faten Hadj Kacem, Mouna Mnif, Fatma Mnif and Mohamed Abid. Hypoglyceamia due to Paranoeplastic Secretion of Insulin in a Patient with Metastasizing Colon Cancer. American Journal of Medical Case Reports. 2015; 3(2):34-36. doi: 10.12691/AJMCR-3-2-4

Abstract

Paraneoplastic hypoglycemia by insulin secreting is rarely described in literature. We review rare cases of paraneoplastic hypoglycemia due to insulin secreting non islet cell tumor diagnosed in a 51 years old patient. This man has an advanced colon cancer with hepatic metastasize. He was admitted in our department for frequent, severe, organic hypoglycemia. Hormonal finding showed elevated serum levels of insulin and c peptide associated with normal serum levels of IGF1 and IGF2. The patient was treated by diet, prednisolone, diazoxid and the metastasize was surgically removed. So that, Hypoglycemia disappeared quickly after the treatment.

Keywords

Paraneoplastic hypoglycemia, colon cancer, insulin, metastasize, IGF1, IGF2

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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