Disseminated Carcinomatosis of Bone Marrow Due to Sigmoid Colon Cancer

Christos Konstantinidis^1, , Panagiotis Varsos¹ and Sotirios Kympouris^1,

¹Surgical Department, Hippocratio General Hospital of Athens, 114 Vasilissis Sofias str, Athens, Region of Attica, Greece

Cite this paper

Christos Konstantinidis, Panagiotis Varsos and Sotirios Kympouris. Disseminated Carcinomatosis of Bone Marrow Due to Sigmoid Colon Cancer. American Journal of Medical Case Reports. 2015; 3(4):102-104. doi: 10.12691/AJMCR-3-4-4

Abstract

Introduction: Disseminated carcinomatosis of the bone marrow (DCBM) caused by colorectal cancer is rarely seen. DCBM is often accompanied with diffuse intravascular coagulation (DIC). Presentation Of Case: A 72-year-old male patient with a history of right nephrectomy three decades ago for referred benign disease, underwent sigmoid colon resection for cancer causing bowel obstruction. The preoperative evaluation revealed elevated values of CA 19-9 and PSA, with no metastatic lesions in abdominal CT. On eighth postoperative day, the patient developed fever with anemia and thrombocytopenia. Bone marrow examination revealed disseminated carcinomatosis caused by colon cancer. The patient deceased on the twenty seventh postoperative day due to the rapid progression of the accompanied disseminated intravascular coagulation. Discussion: Prognosis for patients with cancer who develop disseminated carcinomatosis of bone marrow (DCBM) is poor. Conclusion: In our case, the rapid deterioration of the patient gave us no option for adjuvant chemotherapy. The outcome was fatal. A 72-year-old male patient with a history of right nephrectomy for benign disease underwent sigmoid colon resection for bowel obstruction due to cancer. Tumor markers CA 19-9 and PSA were elevated, with no metastatic lesions in abdominal CT of admission. On eighth postoperative day, the patient developed severe anemia and thrombocytopenia. Bone marrow examination revealed disseminated carcinomatosis caused by colon cancer. The patient deceased on the twenty seventh postoperative day due to the rapid progression of the accompanied disseminated intravascular coagulation.

Keywords

sigmoid colon, cancer, obstruction, disseminated carcinomatosis, disseminated intravascular coagulation

Copyright

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