Cholesterol Granuloma of Sphenoid Sinus: Report of a Rare Case

Samasuk Thammachantha^1, , Pichest Metarugcheep² and Yodkhwan Wattanasen²

¹Department of Pathology, Prasat Neurological Institute, 312 Rajvithi road, Thung phayathai, Rajthewi, Bangkok, Thailand

²Department of Neuroradiology, Prasat Neurological Institute, 312 Rajvithi road, Thung phayathai, Rajthewi, Bangkok, Thailand

Cite this paper

Samasuk Thammachantha, Pichest Metarugcheep and Yodkhwan Wattanasen. Cholesterol Granuloma of Sphenoid Sinus: Report of a Rare Case. American Journal of Medical Case Reports. 2017; 5(2):35-37. doi: 10.12691/AJMCR-5-2-3

Abstract

Cholesterol granuloma is chronic inflammatory lesion of head and neck region, caused by bleeding of mucosal vessels of paranasal sinus. Histologically, the lesion shows aggregate of cholesterol crystals surrounded by foreign-body giant cell reaction. The symptoms vary depending on location of an expansile mass and Magnetic resonance imaging (MRI) are helpful in distinguish this disease from mucocoele. We present a case of cholesterol granuloma in the right sphenoid sinus of a 52-year-old man, with the oculomotor nerve dysfunction but sparing pupillary reflex.

Keywords

cholesterol granuloma, sphenoid sinus, magnetic resonance imaging, mucocoele

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]	Manojlovic S. Cholesterol Granuloma, Middle Ear. In: Volavšek M, editor. Head and Neck Pathology. Springer: 2016. pp. 68-69.
[2]	Kang H, Kim JK, Kim Y. Association of cholesterol granuloma and aspergillosis in the sphenoid sinus. Korean J Radiol 2008; 9(Suppl): S30-3.
[3]	Jaberoo MC, Hassan A, Pulido MA, Saleh HA. Endoscopic endonasal approaches to management of cholesterol granuloma of the petrous apex. Skull base 2010; 20: 375-9.
[4]	Ramani P, Murugesan K , Chandrasekar T, Anuja N. Cholesterol granuloma of maxillary sinus. Int J Oral Max Surg 2006; 35(11): 1063-5.
[5]	Kim DH, Lee SK, Kim CH, Cho HJ. Radiologically unusual presentation of cholesterol granuloma in the sphenoid sinus. Korean J Otorhinolaryngol-Head Neck Surg 2015; 58(9): 641-5.
[6]	Jackler RK, Parker DA. Radiographic differential diagnosis of petrous apex lesions. Am J Otol 1992; 13(6): 561-74.
[7]	Ahmed M, Joseph E, Mani S, Chacko G, Rajshekhar V. Cholesterol granuloma of the sphenoid sinus: An unusual sphenoid sinus lesion. Neurology India 2012; 60(3): 332-3.
[8]	Greeberg JJ, Oot RF, Wismer GL, Davis KR, Goodman ML, Weber AE, et al. Cholesterol granuloma of the petrous apex: MR and CT evaluation. AJNR Am J Neuroradiol 1988; 9: 1205-14.
[9]	Sarioglu S, Pabuççuoglu U, Arzu Topal N. Cholesterol granuloma and aspergilloma of the maxillary sinus. Eur Arch Otorhinolaryngol 2001; 258: 74-6.
[10]	Miyamura S, Yamaguchi S, Tominaga A, Kinoshita Y, Takeda M, Usui S, et al. A case of petrous apex cholesterol granuloma successfully treated with endoscopic endonasal surgery. Hiroshima J Med Sci. 2014; 63(4): 39-42.
[11]	Prasad PV, Satyanarayana MA, Susritha K, Bala TK. Cholesterol granuloma in middle ear and mastoid. A case report. IJSR 2015; 4(5): 125-6.