Granulicatella Elegans Induced Sepsis; A Rare Case of Nutritionally Variant Streptococcal Infection

Ladan Mohammadi¹, Noman Ahmed Jang Khan^2, and Lavanya Vuppu Panghat²

¹Department of Family Medicine, Conemaugh Memorial Medical Hospital, Johnstown, PA, USA

²Department of Internal Medicine, Conemaugh Memorial Hospital, Johnstown, PA, USA

Cite this paper

Ladan Mohammadi, Noman Ahmed Jang Khan and Lavanya Vuppu Panghat. Granulicatella Elegans Induced Sepsis; A Rare Case of Nutritionally Variant Streptococcal Infection. American Journal of Medical Case Reports. 2017; 5(3):77-78. doi: 10.12691/AJMCR-5-3-8

Abstract

Granulicatella genus , a nutritionally mutant variant of viridans streptococci was originally classified as a part of abiotrophia group until 1995 and later in 2000 as a separate genus are considered as a rare cause of blood stream infections. They are part of normal flora of human oral cavity, intestinal and urogenital tracts and are notorious for causing odontogenic infections. We present a rare case of sepsis in a 90 year old male caused by Granulicatella elegans and some of the proposed methods of diagnosis and treatment of this uncommon infection.

Keywords

granulicatella, streptococci, sepsis

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]	Cargill, J.S., Scott, K.S., Gascoyne-Binzi, D., Sandoe. J.A.T. 2012. Granulicatella infection: diagnosis and management. J. Med Microbio. 61: 755-761.
[2]	Abdul- Redha, R. J., Prag, J., Sonksen, U. W., Kemp, M., Andersen, K. & Christensen, J. J (2007). Granulicatella elegans bacteraemia in patients with abdominal infection. Scand J infect Dis. 39, 830-833.
[3]	Senn L. Entenza JM. Greub G, et al. Bloodstream and endovascular infections due to Abiotrophia defectiva and Granulicatella species. BMC Infect Dis. 2006; 6: 9.
[4]	Brouqui P. Raoult D. Endocarditis due to rare and fastidious bacteria. Clin Microbiol Rev. 2001; 14: 177-207.
[5]	Al-Tawfiq, J. A., Kiwan, G. & Murrar, H. (2007). Granulicatella elegans native valve infective endocarditis: case report and review. Diagn Microbiol Infect Dis. 57, 439-441.
[6]	Tung, S. K., Teng, L. J., Vaneechoutte, M., Chen, H. M. & Chang, T.C (2007). Identification of species of Abiotrophia, Enterococcus, Granulicatella and Streptococcus by sequence analysis of the ribosomal 16S-23S intergenic spacer region. J Med Microbiol. 56, 504-513.
[7]	Gescher, D. M., Kovacevic, D., Schmiedel, D., Siemoneit, S., Mallmann, C., Halle, E., Gobel, U. B. & Moter, A. (2008). Flourescence in situ hybridisation (FISH) accelerates identification of Gram-positive cocci in positive blood cultures. Int J Antimicrob Agents. 32 (Suppl. 1), S51-S59.
[8]	Jorgensen, J. H. & Hindler, J. F. (2007). New consensus guidelines from the Clinical and Laboratory Standards Institute for antimicrobial susceptibility testing of infrequently isolates or fastidious bacteria. Clin Infect Dis. 44, 280-286.
[9]	Tuohy, M. J., Procop, G. W. & Washington, J. A. (2000). Antimicrobial susceptibility of Abiotrophia adiacens and Abiotrophia defectiva, Diagn Microbiol Infect Dis. 38, 189-191.
[10]	Habib, G., Hoen, B., Tornos, P., Thuny, F., Prendergast, B., Vilacosta, I., Moreillon, P., de Jesus Antunes, M., Thilen, U., & other authors (2009). Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Eur Heart J. 30, 2369-2413.