Rifabutin low dose-induced intermediate uveitis in a patient with Acquired Immunodeficiency Syndrome

Agustina C. Palacio¹, Mercedes Cabrini², Graciela Ben² and Emilio M. Dodds^1,

¹Department of Ophthalmology, Consultores Oftalmológicos, Buenos Aires, Argentina

²Department of infectology, Hospital General de Agudos Juan A. Fernandez, Buenos Aires, Argentina

Cite this paper

Agustina C. Palacio, Mercedes Cabrini, Graciela Ben and Emilio M. Dodds. Rifabutin low dose-induced intermediate uveitis in a patient with Acquired Immunodeficiency Syndrome. American Journal of Medical Case Reports. 2017; 5(5):116-118. doi: 10.12691/AJMCR-5-5-3

Abstract

Intermediate uveitis is a relatively rare manifestation of Rifabutin induced uveitis. Rifabutin toxicity is unusual at doses of 300 mg daily or less. The purpose of this study is to report the case of an HIV+ patient with unilateral rifabutin induced intermediate uveitis after 4 months of treatment with low dose rifabutin (150 mg daily) in combination with ritonavir and fluconazole. The uveitis resolved after drug discontinuance and the use topical corticosteroids.

Keywords

Rifabutin, drug induced uveitis, intermediate uveitis, vitritis, drug interaction

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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