Unusual presentation of Gastrointestinal Basidiobolomycosis in a 7-year-old Child – Case Report

Hossain Ibrahim Ageel^1, , Haider Mohammed Arishi¹, Ali Abdullah Kamli², Aladdin Mahmoud Hussein³ and Srinivas Bhavanarushi⁴

¹Department of Pediatrics, King Fahd Central Hospital, Jazan, Saudi Arabia

²Department of Radiology, King Fahd Central Hospital, Jazan, Saudi Arabia

³Department of Surgery, King Fahd Central Hospital, Jazan, Saudi Arabia

⁴Department of Histopathology, King Fahd Central Hospital, Jazan, Saudi Arabia

Cite this paper

Hossain Ibrahim Ageel, Haider Mohammed Arishi, Ali Abdullah Kamli, Aladdin Mahmoud Hussein and Srinivas Bhavanarushi. Unusual presentation of Gastrointestinal Basidiobolomycosis in a 7-year-old Child – Case Report. American Journal of Medical Case Reports. 2017; 5(5):131-134. doi: 10.12691/AJMCR-5-5-8

Abstract

Gastrointestinal basidiobolomycosis (GIB) is a rare fungal infection caused by basidiobolus ranarum. It has been recognized increasingly in the southern region of Saudi Arabia. Here, we report an unusual case of pediatric GIB with anorectal involvement in a 7-year-old Yemeni boy living in the south of Saudi Arabia. He had abdominal pain, abdominal distension, rectal bleeding, weight loss, perianal swelling and redness, and peripheral eosinophilia. The abdominal computed tomographic (CT) scan revealed significant wall thickness of the rectum. Histopathological findings of full thickness biopsy were consistent with basidiobolomycosis. The patient was treated with voriconazole and showed marked improvement. This case highlights the importance of considering GIB in children presenting with bleeding per rectum and eosinophilia associated with anorectal mass.

Keywords

basidiobolomycosis, gastrointestinal, basidiobolus ranarum, saudi arabia, voriconazole, splender-hoeppli phenomenon

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]	El-Shabrawi MH, Kamal NM. Gastrointestinal Basidiobolomycosis in children: an overlooked emerging infection. J Med Microbiol 2011; 60: 871-880.
[2]	Shreef K, Saleem M, Saeedd MA, Eissa M. Gastrointestinal Basidiobolomycosis: An Emerging, and A Confusing, Disease in children (A Multicenter Experience). Eur J Pediatr Surg 2017 Feb 6.
[3]	Gugnani HC. A review of zygomycosis due to Basidiobolus ranarum. Eur J Epidemiol 1999; 15: 923-929.
[4]	Mantadakis E, Samonis G. Clinical presentation of zygomycosis. Clin Microbiol Infect 2009; 15 (Suppl 5):15-20.
[5]	Al Jarie A, Al-Mohsen I, Al Jumaah S, Al Hazmi M, Al Zamil F, Al Zahrani M, et al. Pediatric gastrointestinal basidiobolomycosis. Pediatr Infect Dis J 2003; 22(11): 1007-1013.
[6]	Al Jarie A, Al Azraki T, Al-Mohsen I, Al Jumaah S, Almutawa A, Mohd Fahim Y, et al. Basidiobolomycosis: Case series. J Mycol Med 2011; 21(1): 37-45.
[7]	Al-Qahtani SM, Alsuheel AM, Shati AA, et al. Case reports: Gastrointestinal basidiobolomycosis in children. Curr Pediatr Res 2013; 17: 1-6.
[8]	Al-Asmi MM, Faqeehi HY, Alshahrani DA, Al-Hussaini AA. A case of pediatric gastrointestinal basidiobolomycosis mimicking Crohn's disease. A review of pediatric literature. Saudi Med J 2013; 34(10): 1068-1072.
[9]	Zahari P, Hirst RG, Shipton WA, Campbell RS. The origin and pathogenicity of basidiobolus species in Northern Australia. J Med Vet Mycol 1990; 28: 461-468.
[10]	Edington GM, Phycomycosis in Ibadan, Western Nigeria: two post-mortem reports. Trans R Soc Trop Med Hyg 1964; 58: 242-245.
[11]	Al-Naemi AQ, Khan LA, Al-Naemi I, Khadija A , et al. A case report of gastrointestinal basidiobolomycosis treated with voriconazole. Medicine 2015; 94 (35):e1430.
[12]	Wasim YN, Assaf HM, Rotowa NA. Invasive gastrointestinal basidiobolus ranarum infection in an immunocompetent child. Pediatr Infect Dis J 2003; 22(3): 281-282
[13]	El-Shabrawi MH, Kamal NM, Jouini R, Al-Harbi A, Voigt K, Al-Malki T. Gastrointestinal Basidiobolomycosis: an emerging fungal infection causing bowel perforation in a child. J Med Microbiol 2011; 60: 1395-1402.
[14]	Albaradi BA, Babiker AM, Al-Qahtani HS. Successful treatment of gastrointestinal basidiobolomycosis with voriconazole without surgical intervention. J Trop Pediatr 2014; 60(6): 476-479.
[15]	AlSaleem K, Al-Mehaidib A, Banemai M, bin-Hussain I, Faqih M, Al Mehmadi A. Gastrointestinal Basidiobolomycosis: mimicking Crohn’s disease case report and review of the literature. Ann Saudi Med 2013; 33(5): 500-4.
[16]	Al Jarie AA Hilal A, Al-Hayli MR, Sabr ZA, et al. Unusual cause of bleeding per rectum in children - Case report. Int J Cur Res Rev 2016; 8(10): 12-15.
[17]	Al-Dakhil AM, Aljuaid A, Haneef M, et al. Pediatric gastrointestinal basidiobolomycosis: Case series. J Gastrointest Dig Syst 2016, 6:3(Suppl).
[18]	Al-Juaid A, Al-Rezqi A, Almansouri W, et al. Pediatric Gastrointestinal Basidiobolomycosis: Case report and review of Literature. Saudi J Med Med Sci 2017;5:167-71.
[19]	Alahmadi R, Sayadi H, Badreddine S, et al. Gastrointestinal basidiobolomycosis, the experience of a tertiary care hospital in the western region of Saudi Arabia and a report of four new cases. Life Sci J 2014; 11: 344-352.
[20]	Vikram HR, Smilack JD, Leighton JA, et al. Emergence of gastrointestinal basidiobolomycosis in the United States, with a review of worldwide cases. Clin Infect Dis 2012; 54: 1685-1691.
[21]	Fahimzad A, Karimi A, Tabatabaei SR, Zadeh MG. Gastrointestinal basidiobolomycosis as a rare etiology of bowel obstruction. Turk J Med Sci 2006; 36: 239-241.
[22]	Trudea J, Mwango G, Mathaiya J, et al. Unusual presentation of invasive Basidiobolus mycosis as a pelvic mass in a 3-year-old child: a case report. East Cent Afr J Surg 2015; 20(2): 125-131.
[23]	Geramizadeh B, Foroughi R, Keshtkar-Jahromi M, et al. Gastrointestinal basidiobolomycosis, an emerging infection in the immunocompetent host: a report of 14 patients. J Med Microbiol 2012; 61: 1770-1774.