Marijuana Induced Type I Brugada Pattern: A Case Report

Pramod Theetha Kariyanna¹, Apoorva Jayarangaiah², Sudhanva Hegde¹, Jonathan D.Marmur¹, Perry Wengrofsky³, Mena Yacoub⁴, Michael Post³ and Samy I. McFarlane^3,

¹Division of Cardiovascular Disease, Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, N.Y, U.S.A-11203

²Department of Internal Medicine, Wake Forest University, Baptist Health System, Winston-Salem, N.C., U.S.A-27101

³Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, N.Y, U.S.A-11203

⁴Northside Hospital, St. Petersburg, Florida, 33709

Cite this paper

Pramod Theetha Kariyanna, Apoorva Jayarangaiah, Sudhanva Hegde, Jonathan D.Marmur, Perry Wengrofsky, Mena Yacoub, Michael Post and Samy I. McFarlane. Marijuana Induced Type I Brugada Pattern: A Case Report. American Journal of Medical Case Reports. 2018; 6(7):134-136. doi: 10.12691/AJMCR-6-7-4

Abstract

Marijuana is the most common drug of abuse in the United States. Marijuana acts on cannabinoid receptors CB1, CB2 and another distinct endothelial receptor. Marijuana is known to cause tachycardia, hypotension and hypertension. Various arrhythmias including atrial fibrillation, atrial flutter, II degree AV block, ventricular fibrillation, ventricular tachycardia, asystole and brugada pattern associated with marijuana use have been reported. We here present an interesting case of Type I Brugada pattern in electrocardiography (ECG) in a 36 year old healthy African American male who presented after smoking four joints. Urine toxicology test proved marijuana use. Acute coronary syndrome was ruled out, coronary angiogram revealed normal coronaries, 2D echocardiogram showed no evidence of structural heart disease. Upon resolution of Brugada pattern in ECG, procainamide challenge performed in electrophysiology laboratory did not induce Brugada pattern. Patient was asked to return to hospital if he developed fever that did not resolve with antipyretics. Further studies are required to to understand the effect of marijuana on cardiac ion channels.

Keywords

marijuana, cannabis, brugada

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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