Skip Navigation Links.
Collapse <span class="m110 colortj mt20 fontw700">Volume 12 (2024)</span>Volume 12 (2024)
Collapse <span class="m110 colortj mt20 fontw700">Volume 11 (2023)</span>Volume 11 (2023)
Collapse <span class="m110 colortj mt20 fontw700">Volume 10 (2022)</span>Volume 10 (2022)
Collapse <span class="m110 colortj mt20 fontw700">Volume 9 (2021)</span>Volume 9 (2021)
Collapse <span class="m110 colortj mt20 fontw700">Volume 8 (2020)</span>Volume 8 (2020)
Collapse <span class="m110 colortj mt20 fontw700">Volume 7 (2019)</span>Volume 7 (2019)
Collapse <span class="m110 colortj mt20 fontw700">Volume 6 (2018)</span>Volume 6 (2018)
Collapse <span class="m110 colortj mt20 fontw700">Volume 5 (2017)</span>Volume 5 (2017)
Collapse <span class="m110 colortj mt20 fontw700">Volume 4 (2016)</span>Volume 4 (2016)
Collapse <span class="m110 colortj mt20 fontw700">Volume 3 (2015)</span>Volume 3 (2015)
Collapse <span class="m110 colortj mt20 fontw700">Volume 2 (2014)</span>Volume 2 (2014)
Collapse <span class="m110 colortj mt20 fontw700">Volume 1 (2013)</span>Volume 1 (2013)
American Journal of Medical Case Reports. 2018, 6(9), 169-172
DOI: 10.12691/AJMCR-6-9-1
Original Research

Marijuana Induced Myocarditis: A New Entity of Toxic Myocarditis

Pramod Theetha Kariyanna1, Apoorva Jayarangaiah2, Navneet Singh3, Teresa Song3, Stanley Soroka3, Abhimanyu Amarnani3, Justina Ray3 and Samy I. McFarlane3,

1Division of Cardiovascular Disease, Department of Internal Medicine, State University of New York, Downstate Medical Center, Brooklyn, New York, U.S.A- 11203.

2Department of Internal Medicine, Wake Forest University, Baptist Health System, Winston-Salem, North Carolina, U.S.A-27157.

3Department of Internal Medicine, State University of New York Downstate Medical Center, Brooklyn, New York, U.S.A- 11203.

Pub. Date: September 26, 2018

Cite this paper

Pramod Theetha Kariyanna, Apoorva Jayarangaiah, Navneet Singh, Teresa Song, Stanley Soroka, Abhimanyu Amarnani, Justina Ray and Samy I. McFarlane. Marijuana Induced Myocarditis: A New Entity of Toxic Myocarditis. American Journal of Medical Case Reports. 2018; 6(9):169-172. doi: 10.12691/AJMCR-6-9-1

Abstract

Marijuana is the most common drug of abuse in the United States. Marijuana has more than 460 active chemical compounds including δ-9- tetrahydrocannabinol (THC). It acts via the CB1 and CB2 receptors that are distributed in various tissues in the body. Marijuana is known to cause tachycardia, bradycardia, hypertension, to decrease time angina, myocardial infarction and cardiac arrest. Till date, four cases of myocarditis/perimyocarditis associated with marijuana use have been reported. In one such case, it led to the development of heart failure in a young male patient. It is not clear if marijuana in and of itself causes myocarditis/perimyocarditis or if the etio-pathogenesis is actually related to the contaminants in marijuana such as pesticides and heavy metals. We hereby present a young male who with myocarditis related to marijuana use. Clinicians should have suspicion for myocarditis or perimyocarditis in patients presenting with chest pain following marijuana use.

Keywords

marijuana, myocarditis, toxic myocarditis

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]  Substance Abuse and Mental Health Services Administration. (2017). Key substance use and mental health indicators in the United States: Results from the 2016 National Survey on Drug Use and Health (HHS Publication No. SMA 17-5044, NSDUH Series H-52). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration. Retrieved from https://www.samhsa.gov/data/
 
[2]  Azofeifa A, Mattson ME, Schauer G, McAfee T, Grant A, Lyerla R. National Estimates of Marijuana Use and Related Indicators - National Survey on Drug Use and Health, United States, 2002-2014. MMWR Surveill Summ 2016; 65: 1-28.
 
[3]  DEA website accessed on 4/29/2018 Retrieved from: https://www.dea.gov/druginfo/ds.shtml.
 
[4]  PROCON.ORG. 29 legal medical marijuana states and DC: laws, fees, and possession limits. Retreived from: http://medicalmarijuana.procon.org/view.resource.php?resourceID=00088.
 
[5]  Amar, Mohamed Ben. “Cannabinoids in medicine: A review of their therapeutic potential.” Journal of ethnopharmacology105.1-2 (2006): 1-25.
 
[6]  Kattoor A, Mehta JL. Marijuana and coronary heart disease. American College of Cardiology. www.acc.org/latest-in-cardiology/articles/2016/09/22/08/58/marijuana-and-coronary-heart-disease. September 22, 2016. Accessed July 5, 2017.
 
[7]  McLaren, Jennifer, et al. “Cannabis potency and contamination: a review of the literature.” Addiction 103.7 (2008): 1100-1109.
 
[8]  Leontiadis, Evangelos, et al. “Thoratec left ventricular assist device removal after toxic myocarditis.” The Annals of thoracic surgery 86.6 (2008): 1982-1985.
 
[9]  Rodríguez-Castro, Carlos E., et al. “Recurrent myopericarditis as a complication of marijuana use.” The American journal of case reports 15 (2014): 60.
 
[10]  Tournebize, J., et al. “Myocarditis and cannabis: An unusual association.” Toxicologie Analytique et Clinique 28.3 (2016): 236.
 
[11]  Nappe, Thomas M., and Christopher O. Hoyte. “Pediatric Death Due to Myocarditis after Exposure to Cannabis.” Clinical Practice and Cases in Emergency Medicine 1.3 (2017).
 
[12]  Kagen, Steven L., et al. “Marijuana smoking and fungal sensitization.” Journal of allergy and clinical immunology 71.4 (1983): 389-393.
 
[13]  Kurup, V. P., et al. “Allergenic fungi and actinomycetes in smoking materials and their health implications.” Mycopathologia 82.1 (1983): 61-64.
 
[14]  Verweij, Paul E., et al. “Fungal contamination of tobacco and marijuana.” Jama 284. 22 (2000): 2875-2875.
 
[15]  Hazekamp, Arno, Pieter Sijrier, and Rob Verpoorte. “An evaluation of the quality of medicinal grade cannabis in the Netherlands.” Cannabinoids 1.1 (2006): 1-9.
 
[16]  Exley, Christopher, et al. “Aluminum in tobacco and cannabis and smoking-related disease.” The American journal of medicine 119.3 (2006): 276-e9.
 
[17]  StollzNow. Market Research Report: Australians on Cannabis. Report Prepared for NDARC and Pfizer Australia. Sydney: StollzNow Research and Insights Advisory; 2006.
 
[18]  Swift W., Gates P., Dillon P. Survey of Australians using cannabis for medical purposes. Harm Reduct J 2005; 2: 18.
 
[19]  UK Cannabis Internet Activists. Cannabis Contamination. January 2007. Available at: http://www.ukia.org/library/ contam/default.php (accessed 28 June 2007).
 
[20]  Department of Health. Alert-Contamination of Herbal or ‘Skunk-Type’ Cannabis with Glass Beads. 19 January 2007. Available at: http://www.info.doh.gov.uk/doh/embroadcast.nsf/vwDiscussionAll/297D9740D0412C9D802572650050A4A0?OpenDocument.