Skip Navigation Links.
Collapse <span class="m110 colortj mt20 fontw700">Volume 12 (2024)</span>Volume 12 (2024)
Collapse <span class="m110 colortj mt20 fontw700">Volume 11 (2023)</span>Volume 11 (2023)
Collapse <span class="m110 colortj mt20 fontw700">Volume 10 (2022)</span>Volume 10 (2022)
Collapse <span class="m110 colortj mt20 fontw700">Volume 9 (2021)</span>Volume 9 (2021)
Collapse <span class="m110 colortj mt20 fontw700">Volume 8 (2020)</span>Volume 8 (2020)
Collapse <span class="m110 colortj mt20 fontw700">Volume 7 (2019)</span>Volume 7 (2019)
Collapse <span class="m110 colortj mt20 fontw700">Volume 6 (2018)</span>Volume 6 (2018)
Collapse <span class="m110 colortj mt20 fontw700">Volume 5 (2017)</span>Volume 5 (2017)
Collapse <span class="m110 colortj mt20 fontw700">Volume 4 (2016)</span>Volume 4 (2016)
Collapse <span class="m110 colortj mt20 fontw700">Volume 3 (2015)</span>Volume 3 (2015)
Collapse <span class="m110 colortj mt20 fontw700">Volume 2 (2014)</span>Volume 2 (2014)
Collapse <span class="m110 colortj mt20 fontw700">Volume 1 (2013)</span>Volume 1 (2013)
American Journal of Medical Case Reports. 2019, 7(4), 62-66
DOI: 10.12691/AJMCR-7-4-3
Case Report

Duodenal Varix Rupture – A Rare Cause of Fatal Gastrointestinal Hemorrhage: A Case Report and Review of Literature

Sadat Iqbal1, Michelle Likhtshteyn1, Daniel O’Brien1, Samy I. McFarlane1, and Manuel Martinez1, 2

1Department of Internal Medicine, SUNY Downstate Medical Center, Brooklyn, NY, USA

2Department of Gastroenterology, Veterans Affairs Hospital, Brooklyn, NY, USA

Pub. Date: April 24, 2019

Cite this paper

Sadat Iqbal, Michelle Likhtshteyn, Daniel O’Brien, Samy I. McFarlane and Manuel Martinez. Duodenal Varix Rupture – A Rare Cause of Fatal Gastrointestinal Hemorrhage: A Case Report and Review of Literature. American Journal of Medical Case Reports. 2019; 7(4):62-66. doi: 10.12691/AJMCR-7-4-3

Abstract

Duodenal varices are a rare complication of portal hypertension; with cirrhosis being the most common cause. Reports regarding the disease prognosis and natural history are limited. In addition to the diagnostic difficulty, ectopic duodenal varices pose a significant therapeutic challenge owing to the lack of specific management guidelines. Given the high risk of rupture, they can have devastating clinical outcomes. Rupture typically presents as a gastrointestinal hemorrhage and requires emergent interventions. We present a case of duodenal varix seen on upper endoscopy in a patient with portal hypertension and cirrhosis, together with review of the literature outlining the current understanding of this disease entity. We also highlight the pathogenetic mechanisms as well as the current diagnostic and therapeutic approaches for this potentially fatal disease.

Keywords

duodenal varices, gastrointestinal hemorrhage, cirrhosis, portal hypertension

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]  Bhagani S, Winters C, Moreea S. Duodenal variceal bleed: an unusual cause of upper gastrointestinal bleed and a difficult diagnosis to make. BMJ Case Rep. 2017; 2017.
 
[2]  Park SB, Lee SH, Kim JH, et al. Successful treatment of duodenal variceal bleeding by endoscopic clipping. Clin Endosc. 2013; 46(4): 403-6.
 
[3]  Mora-Soler A, Velasco-Guardado A, Acosta-Materan R, et al. Endoscopic treatment of duodenal varices with cyanoacrylate. Rev Esp Enferm Dig. 2013;105(10): 629-32.
 
[4]  Sato T. Treatment of ectopic varices with portal hypertension. World J Hepatol. 2015;7(12): 1601-5.
 
[5]  Tang SJ, Zanati S, Dubcenco E, et al. Diagnosis of small-bowel varices by capsule endoscopy. Gastrointest Endosc. 2004; 60(1): 129-35.
 
[6]  Eisen, Glenn M. et al. “The accuracy of PillCam ESO capsule endoscopy versus conventional upper endoscopy for the diagnosis of esophageal varices: a prospective three-center pilot study.” Endoscopy 38 1 (2006): 31-5.
 
[7]  McCarth T,, Afinogenova, Y Basile, N, Use of Wireless Capsule Endoscopy for the Diagnosis and Grading of Esophageal Varieces in Patients with Portal Hypertension: A Systematic Review and Meta-analysis. J Clin Gastroenterolo. 2017 Feb: 51(2) 174-182.
 
[8]  Roberto de Franchis, on behalf of the Baveno VI Faculty, Expanding consensus in portal hypertension Report of the Vaveno VI Consensus Workshop: Stratifying risk and individualizing care for portal hypertesion Journal of Hepatology, 2015 vol. 63 743-752.
 
[9]  Park SW, Cho E, Jun CH, et al. Upper gastrointestinal ectopic variceal bleeding treated with various endoscopic modalities: Case reports and literature review. Medicine (Baltimore). 2017; 96(1): e5860.
 
[10]  Helmy A, Al Kahtani K, Al Fadda M. Updates in the pathogenesis, diagnosis and management of ectopic varices. Hepatol Int. 2008; 2(3): 322-34.
 
[11]  Gunjan D, Sharma V, Rana SS, Bhasin DK. Small bowel bleeding: a comprehensive review. Gastroenterol Rep (Oxf). 2014; 2(4): 262-75.