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American Journal of Medical Case Reports. 2020, 8(11), 428-430
DOI: 10.12691/AJMCR-8-11-13
Case Report

COVID-19 Vasculitis: A Case Report with Complicated Course

Mousa Suhail Abu Ghoush1, , Mahfoud El. Bashari2, Amani Alzaabi3 and Mohammed Aboelnaga4

1Zayed Military Hospital, Internal Medicine Resident, Abu Dhabi, United Arab Emirates

2Zayed Military Hospital, Consultant Neurology, Abu Dhabi, United Arab Emirates

3Zayed Military Hospital, Consultant and Head of Department Neurology, Abu Dhabi, United Arab Emirates

4Zayed Military Hospital, Specialist Neurology, United Arab Emirates

Pub. Date: July 31, 2020
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Cite this paper

Mousa Suhail Abu Ghoush, Mahfoud El. Bashari, Amani Alzaabi and Mohammed Aboelnaga. COVID-19 Vasculitis: A Case Report with Complicated Course. American Journal of Medical Case Reports. 2020; 8(11):428-430. doi: 10.12691/AJMCR-8-11-13

Abstract

Coronavirus disease 2019 (COVID-19) is a viral infection caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), it spreads from person to person rapidly and presents with multi systemic manifestations namely respiratory symptoms, similar to prior SARS viruses. Neurologic manifestations of COVID-19 are uncommon; those include encephalopathy, strokes, and polyneuropathy. Here we report a unique neurologic complication of COVID-19 in a patient who had extensive cerebral small-vessel ischemic lesions resembling those of cerebral vasculitis. This case report supports the fact that neurologic complications from CVOID 19 could be more debilitating than the respiratory illness itself, especially for those patients who were eventually able to survive the complicated course of being on mechanical ventilation but unfortunately end up with this extensive CNS insult.

Keywords

COVID-19, CNS, Vasculitis

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]  World Health Organization. Novel Coronavirus (2019-nCoV) technical guidance. https://www.who.int/emergencies/diseases/novel-coronavirus- 2019/technical-guidance (Accessed on February 14, 2020).
 
[2]  Endothelial cell infection and endotheliitis in COVID-19.Varga Z, Flammer AJ, Steiger P, Haberecker M, Andermatt R, Zinkernagel AS, Mehra MR, Schuepbach RA, Ruschitzka F, Moch H Lancet. 2020; 395(10234): 1417. Epub 2020 Apr 21.
 
[3]  Monteil V, Kwon H, Prado P, et al. Inhibition of SARS-CoV-2 infections in engineered human tissues using clinical-grade soluble human ACE2. Cell 2020; 181: 905-913. e7 C