American Journal of Medical Case Reports. 2020, 8(12), 471-473
DOI: 10.12691/AJMCR-8-12-10
Early Neurosyphilis in an Immunocompetent Patient: A Case Report
Ankit Dubey1, , Jaspreet Dhanjal1 and Chukwuemeka A. Umeh1
1Department of Internal Medicine, Hemet Valley Medical Center, Hemet, California, USA
Pub. Date: September 03, 2020
Cite this paper
Ankit Dubey, Jaspreet Dhanjal and Chukwuemeka A. Umeh. Early Neurosyphilis in an Immunocompetent Patient: A Case Report.
American Journal of Medical Case Reports. 2020; 8(12):471-473. doi: 10.12691/AJMCR-8-12-10
Abstract
While the prevalence of syphilis had seen a significant decrease in the post-antibiotic era, it can still present in immunocompromised patients. While it is rare for immunocompetent patients to present with advanced stages of Syphilis, prompt recognition and diagnosis is imperative to prevent serious complications. We present the case of a 52 year old immunocompetent female who was diagnosed with syphilis 30 years ago who presented with vague symptoms including a rash, blurred vision, and headache and was diagnosed with early neurosyphilis.
Keywords
neurosyphillis, immunocompetent
Copyright
This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit
http://creativecommons.org/licenses/by/4.0/
References
[1] | Sparling PF. Natural history of syphilis. In: Sexually Transmitted Diseases, Holmes KK, Mardh PA, Sparling PF, et al (Eds), McGraw-Hill, New York 1990. p.213. |
|
[2] | Rosahn PD. Autopsy studies in syphilis. 649 Information supplement #21, J Venereal Disease; U.S. Public Health Service Venereal Disease Division, Washington, DC 1947. |
|
[3] | United States Centers for Disease Control and Prevention. Sexually transmitted disease surveillance, 2018 https://www.cdc.gov/std/stats18/Syphilis.htm (Accessed on October 17, 2019). |
|
[4] | Sexually transmitted diseases treatment guidelines, 2015. Workowski KA, Bolan GA, Centers for Disease Control and Prevention MMWR Recomm Rep. 2015;64(RR-03):1. |
|
[5] | Conde-SendÃn MA, Amela-Peris R, Aladro-Benito Y, Maroto AA. Current clinical spectrum of neurosyphilis in immunocompetent patients. Eur Neurol 2004; 52:29. |
|
[6] | Moradi A, Salek S, Daniel E, et al. Clinical features and incidence rates of ocular complications in patients with ocular syphilis. Am J Ophthalmol 2015; 159:334. |
|
[7] | Oliver SE, Aubin M, Atwell L, et al. Ocular Syphilis - Eight Jurisdictions, United States, 2014-2015. MMWR Morb Mortal Wkly Rep 2016; 65:1185. |
|
[8] | Stokes JH, Beerman H, Ingraham NR. Modern Clinical Syphilology: Diagnosis, Treatment, Case Study, 3rd ed, WB Saunders, Philadelphia 1944. |
|
[9] | Marra CM, Tantalo LC, Maxwell CL, et al. The rapid plasma reagin test cannot replace the venereal disease research laboratory test for neurosyphilis diagnosis. Sex Transm Dis 2012; 39:453. |
|
[10] | Izzat NN, Bartruff JK, Glicksman JM, et al. Validity of the VDRL test on cerebrospinal fluid contaminated by blood. Br J Vener Dis 1971; 47:162. |
|