A Rare Case of Acute Ischemic Hepatitis Secondary to Hepatic Sequestration Crisis in Sickle Cell Disease

Zainab Abbasi^1, , Muhammad Faizan Ahmed², Sejal Neel¹, Amro Elshereye² and Ifeanyichukwu David Onukogu²

¹Internal Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, 76090 Pakistan

²Internal Medicine, Brookdale Hospital Medical Center, Brooklyn, NY, 11212, USA

Cite this paper

Zainab Abbasi, Muhammad Faizan Ahmed, Sejal Neel, Amro Elshereye and Ifeanyichukwu David Onukogu. A Rare Case of Acute Ischemic Hepatitis Secondary to Hepatic Sequestration Crisis in Sickle Cell Disease. American Journal of Medical Case Reports. 2020; 8(12):496-497. doi: 10.12691/AJMCR-8-12-18

Abstract

Acute Ischemic Hepatitis in sickle cell disease could lead to acute hepatic failure. The term Sickle Cell Hepatopathy encompasses a wide range of hepatic manifestations that occur due to this disease itself or secondary to treatment. Although our patient had a homozygous inheritance for the sickle cell gene but never experienced any hepatic complications of the disease. Our patient experienced an acute hepatic sequestration crisis which otherwise usually occurs in the spleen. This case signifies the importance of early evaluation and management of hepatic involvement in sickle cell disease to prevent overt hepatic failure.

Keywords

sickle cell disease, hepatic sequestration crisis, acute ischemic hepatitis, acute abdominal pain, exchange transfusion

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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