Primary Ovarian Non-Hodgkin’s Lymphoma with Late Diagnosis Due to Unusual Presentation - A Case Report

Ferdous Ara Begum^1, , Md Arifur Rahman¹, Mohammed Kamal² and Qamruzzaman Chowdhury¹

¹Department of Oncology, Bangladesh Specialized Hospitals, 21 Shyamoli, Dhaka, Bangladesh

²The Labratory, Panthapath, Dhaka, Bangladesh

Cite this paper

Ferdous Ara Begum, Md Arifur Rahman, Mohammed Kamal and Qamruzzaman Chowdhury. Primary Ovarian Non-Hodgkin’s Lymphoma with Late Diagnosis Due to Unusual Presentation - A Case Report. American Journal of Medical Case Reports. 2020; 8(8):240-243. doi: 10.12691/AJMCR-8-8-7

Abstract

Involvement of NHL in ovary is seen in disseminated Lymphoma but primary ovarian lymphoma still not commonly seen. We presented the case where the patient had suffered for unexplained fever for more than 1 year and lately presented with gross weight loss as well as painless lower abdominal lump. CT scan showed a huge heterogeneous mass of about 15x12.4cm in pelvic cavity with mild ascites. Surgery was performed in view of ovarian neoplasm as CA125 was also raised. Histopathology confirmed the diagnosis of diffuse large B cell lymphoma with Immunohistochemistry confirmation. Treated with R-CHOP protocol for 6 cycles as IHC expressed CD20 positive. Post chemotherapy follow up PET scan showed complete response of treatment, though in spite of all treatment Primary ovarian lymphoma have a poor outcome with a range from 0% to 36% expected to survive for less than three years.

Keywords

primary ovarian non-hodgkin’s lymphoma, late diagnosis

Copyright

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