Cushing Syndrome Due to Pigmented Nodular Adrenal Hyperplasia in an Iranian Patient: A Case Report and Review of the Literature

Kamyar Asadipooya¹, Roohollah Narimani², Ashraf Aminorroaya², Bijan Iraj‬², Mohammadreza Kalantarhormozi^3, , Novin Afshar Moghadam⁴, Elaheh Kavoussi³ and Mitra Dashtizadeh‬‬‬³

¹Division of Endocrinology and Molecular Medicine, Department of Medicine, University of Kentucky, Lexington, Kentucky

²Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

³Department of Internal Medicine, School of Medicine, Bushehr University of Medical Sciences, Bushehr, IRAN

⁴Department of pathology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, IRAN

Cite this paper

Kamyar Asadipooya, Roohollah Narimani, Ashraf Aminorroaya, Bijan Iraj‬, Mohammadreza Kalantarhormozi, Novin Afshar Moghadam, Elaheh Kavoussi and Mitra Dashtizadeh‬‬‬. Cushing Syndrome Due to Pigmented Nodular Adrenal Hyperplasia in an Iranian Patient: A Case Report and Review of the Literature. American Journal of Medical Case Reports. 2021; 9(10):492-494. doi: 10.12691/AJMCR-9-10-3

Abstract

Primary pigmented nodular adrenocortical disease (PPNAD) is a rare cause of Adrenocorticotropic hormone-independent Cushing syndrome. In this case, we present a case of PPNAD in 25 y/o women who presented with a 3 years history of weight gain, hirsutism, and abnormal menstruation. Our findings were suggestive of PPNAD in the pathological study of adrenal biopsy.

Keywords

Cushing syndrome, PPNAD, Primary pigmented nodular adrenocortical, hirsutism, low dose dexamethasone suppression test

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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