American Journal of Medical Case Reports. 2021, 9(12), 690-692
DOI: 10.12691/AJMCR-9-12-7
Lymphocyte-predominant Hodgkin’s Lymphoma: A Case Report of a Unique Large Tumor that Involving Breast and Axillary Tissue
Mehdi Seyedmoradi1, Niloufar Mohamadian1 and Mazaher Ramezani2, 3,
1Young Researchers and Elite Club, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran
2Molecular Pathology Research Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
3Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran
Pub. Date: September 05, 2021
Cite this paper
Mehdi Seyedmoradi, Niloufar Mohamadian and Mazaher Ramezani. Lymphocyte-predominant Hodgkin’s Lymphoma: A Case Report of a Unique Large Tumor that Involving Breast and Axillary Tissue.
American Journal of Medical Case Reports. 2021; 9(12):690-692. doi: 10.12691/AJMCR-9-12-7
Abstract
Lymphocyte-predominant Hodgkin’s lymphoma (LPHL) that involving the breast and axillary tissue is very rare. We report a case of this subtype of Hodgkin’s lymphoma (HL) in right breast mass of a 48-year-old man, who presented with a 20 years history of this breast painless mass; but over the past year there has been an increase in the size of the mass, with pain but no discharge. Pathology report after immunohistochemistry (IHC) confirmed the LPHL.
Keywords
Hodgkin’s lymphoma, Lymphocyte-predominant Hodgkin’s lymphoma, LPHL
Copyright
This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit
http://creativecommons.org/licenses/by/4.0/
References
[1] | Saarinen S, Pukkala E, Vahteristo P, Mäkinen MJ, Franssila K, Aaltonen LA. (2013). High familial risk in nodular lymphocyte-predominant Hodgkin lymphoma. J Clin Oncol; 31: 938-943. |
|
[2] | Jackson C, Sirohi B, Cunningham D, Horwich A, Thomas K, Wotherspoon A (2010). Lymphocyte-predominant Hodgkin lymphoma-clinical features and treatment outcomes from a 30-year experience. Annals of Oncology; 21: 2061-2068. |
|
[3] | Lee, A.I. & LaCasce, A.S. (2009). Nodular lymphocyte predominant Hodgkin lymphoma. The Oncologist; 14: 739-751. |
|
[4] | Al-Mansour M, Connors JM, Gascoyne RD, Skinnider B, Savage KJ. (2010). Transformation to aggressive lymphoma in nodular lymphocyte-predominant Hodgkin’s lymphoma. J Clin Oncol; 28: 793-799. |
|
[5] | Nogová L, Reineke T, Brillant C, Sieniawski M, Rüdiger T, Josting A, Bredenfeld H, Skripnitchenko R, Müller RP, Müller-Hermelink HK, Diehl V, Engert A. (2008). Lymphocyte-predominant and classical Hodgkin’s lymphoma: a comprehensive analysis from the German Hodgkin Study Group. J Clin Oncol; 26: 434-439. |
|
[6] | Eichenauer DA, Engert A (2017). Nodular lymphocyte-predominant Hodgkin lymphoma: a unique disease deserving unique management. Hematology Am Soc Hematol Educ Program; 2017: 324-328. |
|
[7] | von Wasielewski R, Werner M, Fischer R, Hansmann ML, Hubner K, Hasenclever D, Franklin J, Sextro M, Diehl V, Georgii A. (1997). Lymphocyte-predominant Hodgkin’s disease: an immunohistochemical analysis of 208 reviewed Hodgkin’s disease cases from the German Hodgkin Study Group. Am J Pathol; 150: 793-803. |
|
[8] | Thodou E, Befani M, Triantafyllidis G, Choreftaki T, Kanellis G, Giannakoulas N. (2019). Hodgkin lymphoma mimicking inflammatory breast carcinoma: A rare case with diagnostic challenge and novel treatment. Case Reports in Hematology; 2019: Article ID 9256807. |
|
[9] | Talwalkar SS, Miranda RN, Valbuena JR, Routbort MJ, Martin AW, Medeiros LJ. (2008). Lymphomas involving the breast: A study of 106 cases comparing localized and disseminated neoplasms. Am J Surg Pathol; 32: 1299-1309. |
|
[10] | Mukherjee R, Mondal M, Banerjee D, Mukherjee M. (2015). Hodgkin’s lymphoma of the breast: a rare occurrence. Clin Cancer Invest J; 4(2): 282-5. |
|
[11] | Hoimes CJ, Selbst MK, Shafi NQ, Rose MG, Rosado MF. (2010). Hodgkin's lymphoma of the breast. J Clin Oncol; 28: e11-3. |
|
[12] | Meis JM, Butler JJ, Osborne BM. (1986). Hodgkin's disease involving the breast and chest wall. Cancer; 57: 1859-65. |
|
[13] | Osuji CU, Ahaneku GI, Onwubuya EI, Okocha EC, Ukah C, Emegoakor CD, Omejua EG. (2013). Hodgkin’s lymphoma of the breast. J Cancer Res Ther; 9: 526-8. |
|