Skip Navigation Links.
Collapse <span class="m110 colortj mt20 fontw700">Volume 12 (2024)</span>Volume 12 (2024)
Collapse <span class="m110 colortj mt20 fontw700">Volume 11 (2023)</span>Volume 11 (2023)
Collapse <span class="m110 colortj mt20 fontw700">Volume 10 (2022)</span>Volume 10 (2022)
Collapse <span class="m110 colortj mt20 fontw700">Volume 9 (2021)</span>Volume 9 (2021)
Collapse <span class="m110 colortj mt20 fontw700">Volume 8 (2020)</span>Volume 8 (2020)
Collapse <span class="m110 colortj mt20 fontw700">Volume 7 (2019)</span>Volume 7 (2019)
Collapse <span class="m110 colortj mt20 fontw700">Volume 6 (2018)</span>Volume 6 (2018)
Collapse <span class="m110 colortj mt20 fontw700">Volume 5 (2017)</span>Volume 5 (2017)
Collapse <span class="m110 colortj mt20 fontw700">Volume 4 (2016)</span>Volume 4 (2016)
Collapse <span class="m110 colortj mt20 fontw700">Volume 3 (2015)</span>Volume 3 (2015)
Collapse <span class="m110 colortj mt20 fontw700">Volume 2 (2014)</span>Volume 2 (2014)
Collapse <span class="m110 colortj mt20 fontw700">Volume 1 (2013)</span>Volume 1 (2013)
American Journal of Medical Case Reports. 2021, 9(3), 153-154
DOI: 10.12691/AJMCR-9-3-5
Letter To Editor

Lacosamide Induced Bradycardia

Mohamedanwar Ghandour1, , Heba Osman2, Samer Alkassis3, Yahya Osman-Malik4 and Zeenat Y. Bhat4

1Department of Internal Medicine, Nephrology Division, Wayne State University/Detroit medical Center, Michigan, USA

2Department of Internal Medicine/Pediatrics, Wayne State University/Detroit Medical Center, Michigan, USA

3Department of Internal Medicine, Wayne State University/Detroit Medical Center, Michigan, USA

4Department of Internal Medicine WSU SOM, Division of Nephrology Wayne State University, Michigan, USA

Pub. Date: January 04, 2021
Full Text PDF

Cite this paper

Mohamedanwar Ghandour, Heba Osman, Samer Alkassis, Yahya Osman-Malik and Zeenat Y. Bhat. Lacosamide Induced Bradycardia. American Journal of Medical Case Reports. 2021; 9(3):153-154. doi: 10.12691/AJMCR-9-3-5

Abstract

Lacosamide (LCM)is an anti-epileptic drug associated with a serious cardiac event. Herein, we report a case of a 45-year-old male patient with lacosamide induced-bradycardia.

Keywords

Lacosamide, bradycardia

Copyright

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]  Kellinghaus C. (2009). Lacosamide as treatment for partial epilepsy: mechanisms of action, pharmacology, effects, and safety. Ther Clin Risk Manag 5: 757-766.
 
[2]  Degiorgio CM. (2010) Atrial flutter/atrial fibrillation associated with lacosamide for partial seizures. Epilepsy Behav 18: 322-324.
 
[3]  Nizam A, Mylavarapu K, Thomas D, Briskin K, Wu B, Saluja D, Wong S. (2011) Lacosamide‐induced second‐degree atrioventricular block in a patient with partial epilepsy. Epilepsia 52: e153-e155.
 
[4]  Shaibani A, Fares S, Selam JL, Arslanian A, Simpson J, Sen D, Bongardt S. (2009). Lacosamide in painful diabetic neuropathy: an 18‐week doubleblind placebo‐controlled trial. J Pain 10: 818-828.
 
[5]  Ben‐Menachem E, Biton V, Jatuzis D, Abou‐Khalil B, Doty P, Rudd GD. (2007) Efficacy and safety of oral lacosamide as adjunctive therapy in adults with partial‐onset seizures. Epilepsia 48: 1308-1317.
 
[6]  Krause LU, Brodowski KO, Kellinghaus C. (2011) Atrioventricular block following lacosamide intoxication. Epilepsy Behav 20: 725-727.
 
[7]  Wymer JP, Simpson J, Sen D, Bongardt S. (2009) Efficacy and safety of lacosamide in diabetic neuropathic pain: an 18‐week double‐blind placebo‐controlled trial of fixed‐dose regimens. Clin J Pain 25: 376-385.