Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome: When the Medication is the Cause!!!

Nicola Jackson^1, , Alain Morel¹, Alicia Pollard¹, Shion Betty¹ and James Appiah-Pippim¹

¹Piedmont Athens Regional Hospital, United States

Cite this paper

Nicola Jackson, Alain Morel, Alicia Pollard, Shion Betty and James Appiah-Pippim. Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome: When the Medication is the Cause!!!. American Journal of Medical Case Reports. 2021; 9(7):375-377. doi: 10.12691/AJMCR-9-7-9

Abstract

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is an idiosyncratic, potentially life-threatening hypersensitivity reaction to therapeutic medication. [1] The most common culprits historically being anticonvulsants followed by antibiotics, but most recent publications are beginning to show the opposite trend. [1] This case describes a 58-year-old-woman who presented for evaluation of a generalized skin rash associated with facial edema 4 weeks after treatment for Methicillin-resistant Staphylococcus aureus pneumonia with empyema.

Keywords

DRESS syndrome, vancomycin

Copyright

This work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

References

[1]	Choudhary S, McLeod M, Torchia D, et al. Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome. J Clin Aesthet Dermatol. 2013; 6(6): 31-37.
[2]	De A, Rajagopala M, Sarda A and Das S. et al. Drug Reaction with Eosinophilia and Systemic Symptoms: An Update and Review of Recent Literature. Indian J Dermatol. 2018 Jan-Feb; 63(1): 30-40.
[3]	Sharifzadeh S, Mohammadpour AH, Tavanaee A, et al. Antibacterial antibiotic-induced drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a literature review. Eur J Clin Pharmacol. 2020 Oct 6: 1-15.